5.6 Vaccination Flashcards
What is immunity
The ability of an organism to resist infection
What are the two forms of immunity
- Passive immunity
2. Active immunity
What is passive immunity
Immunity produced by the introduction of antibodies into individuals from an outside source. No direct contact with the pathogen or its antigen is necessary to induce immunity.
No antibodies are produced, no memory cells are formed.
What is an example of passive immunity
Anti-venom given to the victims, antibodies from the placenta to a fetus from a mother
What is active immunity
Immunity produced by stimulating the production of antibodies by the individuals own immune system, direct contact with the pathogen or its antigen is necessary
What are the two types of active immunity
Natural active immunity - Results from an individual being infected with a disease under normal circumstances
Artificial active immunity - Forms the basis of vaccination. Involves inducing an immune response without suffering symptoms of the disease
What is a vaccination
The introduction of the appropriate disease antigens into the body, either by injection of by mouth.
What is the intention of a vaccination
To stimulate an immune response
What is the basis behind a vaccination
The production of memory cells which remain in the blood and allow a greater, and more immediate, response to a future infection with the pathogen. The result is a rapid production of antibodies and the infection is overcome
What are the features of a successful vaccination programme
- Must be economically viable
- Few side effects
- Methods of producing, storing and transporting the vaccine
- There must be the means of administering the vaccine properly
- Must be possible to vaccinate a large majority of the population to produce her dimmunity
What is herd immunity
Herd immunity arises when a sufficiently large proportion of the population has been vaccinated to make it difficult for a pathogen to spread within that population.
Why may vaccination not eliminate a disease
- Vaccination fails to induce immunity in certain individuals, like those with faulty immune systems
- Individuals may develop the disease immediately after vaccination. These may harbour the disease and reinfect others
- The pathogen may mutate often
- May be varieties of a particular pathogen that it is impossible to develop a vaccine that is effective against all
- Certain pathogens hide from the bodys immune system
- Individuals may have objections to vaccinations for ethical, religious or medical reasons
What are the ethics of using vaccines
- Thee production of existing vaccines involves the use of animals. Is this acceptable
- Vaccines have side-effects that can sometimes cause long-term harm
- Who should vaccines be tested on, how should trials be carried out