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MTAP 2 Blood Banking Part 1 > 5.1 ISBT 004 (Rh Blood Group) > Flashcards

5.1 ISBT 004 (Rh Blood Group) Flashcards

1
Q

Rh Blood Group comes from What chromosome?

A

Chromosome 1

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2
Q

Rh Blood group is ___ most important Blood group

A

2nd

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3
Q

Rh antigen is discovered from?

A

Rhesus Monkey

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4
Q

Rh Antibody was discovered from?

A

Guinea pig and Rabbit

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5
Q

Chromosome # for MNS?

A

4

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6
Q

1st Case related to Rh Blood Group includes Acute Hemolytic Transfusion Reaction from pregnant woman

T or F

A

T

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7
Q

Order of Immunogenicity in Rh group?

A

D > c > E > C >e

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8
Q

Theory of Multiple Allelomorphic genes occuring at a SINGLE Chromosomal Loci

A

Wiener Theory

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9
Q

Theory of pairs of Linked Gene, the antigens of the system were produced by THREE CLOSELY linked sets of Alleles

A

Fisher Race

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10
Q

▪ D gene -> D antigen
▪ C/c gene -> C/c
▪ E/e gene -> E/e

What Theory is this?

A

Fisher Race Theory

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11
Q

Rh genes -> Rho, rh’, rh”

What theory is this?

A

Wiener Theory

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12
Q

What is the Shorthand designation for Rho?

A

Ro

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13
Q

What is the Shorthand designation for rhy?

A

ry

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14
Q

What is the Wiener Agglutination for Rh1

A

Rh1

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15
Q

What is the Fisher Race Antigens for Rhz

A

DCE

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16
Q

What is the Fisher Race Antigens for rhy?

A

CE

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17
Q

What is the Fisher Race Antigens for rh”?

A

cE

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18
Q

What is the Fisher Race Antigens for Rh1?

A

DCe

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19
Q

What is the Fisher Race Antigens for rh?

A

ce

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20
Q

What is the Wiener Blood factors for Rh1

A

Rho rh’ hr”

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21
Q

What is the Wiener Blood factors for Rhz?

A

Rho rh’ rh”

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22
Q

What is the Wiener Blood factors for rh”?

A

hr’ rh”

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23
Q

What is the Wiener Blood factors for rhy?

A

rh’ rh”

24
Q

What is the Rosenfield for Rho?

A

1, -2, -3, 4, 5

25
Q

What is the Rosenfield for Rhz?

A

1, 2, 3, -4, -5

26
Q

What is the Rosenfield for rh”?

A

-1, -2, 3, 4, -5

27
Q

What is the Rosenfield for rh?

A

-1, -2, -3, 4, 5

28
Q

What is the Rosenfield for Rh2?

A

1, -2, 3, 4, -5

29
Q

What is the Rosenfield name if the mother “DCE” and the father “dce”?

A

1, 2, 3, 4, 5

30
Q

● Mother = DCE/DcE
● Father = dCe/dce

Which of the following is not an offspring?
a. r/Rz
b. R2/r
c. Rz/r
d. Rz/R2

A

d

31
Q

Which genotype is heterozygous for “C”
a. Ro / R1
b. r / r”
c. R1/Rz
d. R2 / r”

A

a

32
Q

If a patient develops anti-“c”, what is the genotype?

A

“C”

33
Q

Which donor unit is selected if the recipient has anti-“c” and Anti-“e”?

a. Ro
b. R1
c. R2
d. Rz

A

d

34
Q

Genetics for Rh are inherited as codominant alleles

T or F

A

T

35
Q

Genetic Weak D has a weak D with no antibodies created

T or F

A

T

36
Q

Parenthesis such as (D), (C), (E), indicates strong antigens

T or F

A

F

Weark

37
Q

C trans is position effect is where one genotype has capital C while the other is small c

T or F

A

T

38
Q

PArtial D (D mosaic) is where parts of “D” is Missing which creates antibodies

T or F

A

T

39
Q

What is the Test for Weak D or Partial D?

A

Indirect Antiglobuin test

40
Q

Reporting: A+
Ab screening: Anti D negative

a. Partial D
b. Genetic weak D

A

b

41
Q

Reporting: A+
Ab screening: Anti D Positive

a. Partial D
b. Genetic weak D

A

a

42
Q
A
43
Q

An emergency situation where an Indirect antiglobulin test will not be possible at the moment, what blood type should you release after blood typing these 2?

a. O+
b. O-

A

b

44
Q

In Reporting:

If the patient has weak D, how should you report for Rh?

A

Negative

45
Q

In Reporting:

If the Donor has weak D, how should you report for Rh?

A

Positive

46
Q

In HDFN :

Mother = D _
Fetus = D _

A

-
+

47
Q

In HDFN:

When the mother is in labor, the uterus will be teared causing the baby RBCs (with Rh positive) to enter the blood stream of the mother causing to create anti-D

T or F

A

T

48
Q

Anti-D is IgM

T or F

A

F

IgG

49
Q

IgG is warm reacting

T or F

A

T

50
Q

In HDFN:

When Anti-D sensitize with Fetal RBC, the RBC will pop

T or F

A

F

The Sensitized Fetal RBC will TRY to enter the splenic filter of the fetus but is instead eaten by the macrophage

51
Q

HDFN is intravascular hemolysis

T or F

A

F

Extravascular hemolysis

52
Q

How to extract fetal blood for testing of fetal blood?

A

Cordocentesis

53
Q

HDFN has complement activation

T or F

A

F

No complement activation

54
Q

HDFN occurs when mother is _______ and the fetus is_____

A

D-
D+

55
Q

The possibility of the 1st born to have HDN if:
- The mother has Anti-D due to transfusion
- Abdominal trauma the lead to destruction of placenta

T or F

A

t

56
Q

What are the HDN antibodies?

A

Anti-Kell (K)
Anti-Duffy (a)

MTAP 2 Blood Banking Part 1 (18 decks)

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