11.1 ISBT 027 (Ii)

Question 1

Which among “I” and “i” is more prevalent?

Answer 1

Both

Question 2

In the Newborn, which among “I” or “i” it more prevalent?

Answer 2

i

Question 3

What part of the newborn is rich in “i”?

Use to detect “i” in newborn

Answer 3

Umbilical Cord (Cord blood)

Question 4

In the Adult, which among “I” or “i” it more prevalent?

Answer 4

I

Question 5

Adulit with “i” is rare

T or F

Answer 5

T

Question 6

” I^T “, “T” is known as?

Answer 6

Transition

Question 7

I^T is not “I” or “i”

T or F

Answer 7

T

Question 8

I^T is a transition between “i” to “I”

T or F

Answer 8

T

Question 9

Anti-I : Weak
Anti-i : Strong
Anti-I^T : Strong

What phenotype is this?

Answer 9

Cord

Question 10

Anti-I : Strong
Anti-i : Weak
Anti-I^T : Weak

What phenotype is this?

Answer 10

Adult I

Question 11

Anti-I : Weak
Anti-i : Strong
Anti-I^T : Weakest

What phenotype is this?

Answer 11

Adult i

Question 12

Ii antigen is enhance by enzymes

T or F

Answer 12

T

Question 13

Anti-I causes Malignant Autoagglutination

T or F

Answer 13

F

Benign

Question 14

Autoagglutination for Anti-I causes at what temp in ALL sera?

Answer 14

4 C (or at most 30-32)

Body Temp is 37C so it may not cause autoagglutination unless there is a change in temp

Question 15

Disease association:

Autoanti I can be associated with what organisms?

Answer 15

M. pneumoniae

Question 16

This organisms has a I-Like Ag which can cause production of AutoAnti I in your body

Answer 16

Mycoplasma pneumoniae

Question 17

Autoanti i can be seen in what disease associated?

Answer 17

Infectious Mononucleosis (EBV)

Question 18

Disease associated:

Increase i Antigen is a disease with Long Marrow time

T or F

Answer 18

F

Shortened

Question 19

Increased i antigen can be seen in HEMPAS meaning?

Answer 19

Hereditary Erythroblastic Multinuclearity Positive Acidified Serum Test

Question 20

Adult i phenotype can be seen in _____________ on ASIAN?

Answer 20

Congenital cataracts