3.1 ISBT 002 (MNS) Flashcards
Who discover MN?
a. Landsteiner
b. Levine
c. Walsh
d. Montgomery
a and b
Who discover S?
a. Landsteiner
b. Levine
c. Walsh
d. Montgomery
c and d
Chromosome that creates MNS?
Chromosome 4
MNSs is well developed at _______
Birth
Term for Antibody that reacts better with HOMOZYGOUS antigen
Dosage effect
MNSs has dosage effect
T or F
T
Anti M will react 3+ with ____________ and 2+ with _____________
a. M+, N-
b. M+, N+
c. M-, N-
d. M-, N+
a
b
What are the antigens with Dosage effects?
Dosage:
- Kidd
- Lutheran
- MN
- Duffy
- Rh (Except D)
Those kids loot my Duffy rrr
MN antigen is located on?
a. Glycophorin A
b. Glycophorin B
c. Glycophorin C
d. Glycophorin D
a
MN antigen are affected by?
a. Proteins
b. Enzymes
c. WBC
d. Sialic acid
b
If MN atigen is exposed to enzymes, the sialic acid will be _________ destroying the MN
Remove
In MNS (antigen):
If:
Ptx serum + Reagent cell = _______
Ptx serum + Enzyme treatement RBC cell = _________
Agglutination
No Reaction
What are the Antigens that are enhance by enzymes?
- ABO
- P
- Rh
- I
- Kidd
- Lewis
APRIKidlLE / RIP ALK
Serum + Enzyme treated RBCs = 4+
a. Anti Rh
b. Anti Duffy
a
Serum + Enzyme treated RBCs = 0
a. Anti k
b. Anti I
a
Anti M reacts better with (M+ N-) than (M+ N+)
T or F
T
Anti M reacts best at what pH?
pH 6.5 (Acid, Maasim)
Anti M reacts better When RBCs are exposed to _______ than Fresh blood
Glucose
Anti-N is seen in _______ patients who were dialyzed on equipment sterilized with ___________
Renal
formaldehyde
Formaldehyde is used to clean the dialysis however the residue of formaldehyde may transfer to the next patient which may form what antibody?
a. Anti-N
b. Anti-formaldehyde
c. Anti-M
d. Anti-S
A and B
Ss antigen is located on?
a. Glycophorin A
b. Glycophorin B
c. Glycophorin C
d. Glycophorin D
b
U phenotype is located on?
a. Glycophorin A
b. Glycophorin B
c. Glycophorin C
d. Glycophorin D
b
If the patient has no glycophorin B, the patient naturally produce Anti S, Anti-s and Anti-U
T or F
F
Not naturally occuring, antibodies are produce after exposure. The only naturally occurring are ABO
Glycophorin A and Glycophorin B has a receptor for ___________ which leads to infection
P. falciparum
Dosage effect reacts better with ____________ antigen
Homozygous
