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MTAP 2 Blood Banking Part 1 > 3.1 ISBT 002 (MNS) > Flashcards

3.1 ISBT 002 (MNS) Flashcards

1
Q

Who discover MN?

a. Landsteiner
b. Levine
c. Walsh
d. Montgomery

A

a and b

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2
Q

Who discover S?

a. Landsteiner
b. Levine
c. Walsh
d. Montgomery

A

c and d

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3
Q

Chromosome that creates MNS?

A

Chromosome 4

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4
Q

MNSs is well developed at _______

A

Birth

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5
Q

Term for Antibody that reacts better with HOMOZYGOUS antigen

A

Dosage effect

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6
Q

MNSs has dosage effect

T or F

A

T

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7
Q

Anti M will react 3+ with ____________ and 2+ with _____________

a. M+, N-
b. M+, N+
c. M-, N-
d. M-, N+

A

a
b

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8
Q

What are the antigens with Dosage effects?

A

Dosage:
- Kidd
- Lutheran
- MN
- Duffy
- Rh (Except D)

Those kids loot my Duffy rrr

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9
Q

MN antigen is located on?

a. Glycophorin A
b. Glycophorin B
c. Glycophorin C
d. Glycophorin D

A

a

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10
Q

MN antigen are affected by?

a. Proteins
b. Enzymes
c. WBC
d. Sialic acid

A

b

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11
Q

If MN atigen is exposed to enzymes, the sialic acid will be _________ destroying the MN

A

Remove

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12
Q

In MNS (antigen):

If:
Ptx serum + Reagent cell = _______
Ptx serum + Enzyme treatement RBC cell = _________

A

Agglutination

No Reaction

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13
Q

What are the Antigens that are enhance by enzymes?

A
  • ABO
  • P
  • Rh
  • I
  • Kidd
  • Lewis

APRIKidlLE / RIP ALK

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14
Q

Serum + Enzyme treated RBCs = 4+

a. Anti Rh
b. Anti Duffy

A

a

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15
Q

Serum + Enzyme treated RBCs = 0

a. Anti k
b. Anti I

A

a

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16
Q

Anti M reacts better with (M+ N-) than (M+ N+)

T or F

A

T

17
Q

Anti M reacts best at what pH?

A

pH 6.5 (Acid, Maasim)

18
Q

Anti M reacts better When RBCs are exposed to _______ than Fresh blood

A

Glucose

19
Q

Anti-N is seen in _______ patients who were dialyzed on equipment sterilized with ___________

A

Renal

formaldehyde

20
Q

Formaldehyde is used to clean the dialysis however the residue of formaldehyde may transfer to the next patient which may form what antibody?

a. Anti-N
b. Anti-formaldehyde
c. Anti-M
d. Anti-S

A

A and B

21
Q

Ss antigen is located on?

a. Glycophorin A
b. Glycophorin B
c. Glycophorin C
d. Glycophorin D

A

b

22
Q

U phenotype is located on?

a. Glycophorin A
b. Glycophorin B
c. Glycophorin C
d. Glycophorin D

A

b

23
Q

If the patient has no glycophorin B, the patient naturally produce Anti S, Anti-s and Anti-U

T or F

A

F

Not naturally occuring, antibodies are produce after exposure. The only naturally occurring are ABO

24
Q

Glycophorin A and Glycophorin B has a receptor for ___________ which leads to infection

A

P. falciparum

25
Q

Dosage effect reacts better with ____________ antigen

A

Homozygous

MTAP 2 Blood Banking Part 1 (18 decks)

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