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MTAP 2 Blood Banking Part 1 > 2.4 ISBT 001 (ABO typing discrepancies) > Flashcards

2.4 ISBT 001 (ABO typing discrepancies) Flashcards

1
Q

ABO incompatibility has a weak reaction

T or F

A

F

Strong reaction

4+
3+

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2
Q

Discrepancy when it comes to reaction in ABO are weak reaction

T or F

A

T

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3
Q

Group 1 discrepancy has _______ weak or absent reaction

A

Antibody

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4
Q

Group 1 discrepancy involves problem in __________ typing

A

Reverse

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5
Q

Group 1 discrepancy is cause from Lack of plasma cell or thymus

T or F

A

T

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6
Q

Condition involve in Group 1 discrpancy?

A

Agammaglobulinemia
Hypogammaglobulinemia
Too young or too old

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7
Q

Lymphocytic leukemia Can cause Group 1 Discrepancy

T or F

A

T

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8
Q

Performing Reverse typing in infants can have reaction in Forward typing and not reverse typing

T or F

A

T

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9
Q

What is the Remedy for Group 1 discrepancy?

A
  • Check age
  • Check patient history
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10
Q

Remedy for Hypogammaglobulinemia in Group 1 Discrepancy?

A
  • Prolonged incubation (15-30 mins)
  • Add more serum
  • Incubate in cold temp (4 C) since it is IgM
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11
Q

Group 2 discrepancy involves weak or absent?

A

Antigen

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12
Q

________ typing is the problem cause by Group 2 discrepancy

A

Forward

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13
Q

Subgroup of A and B can cause what discrepancy?

A

Group 2

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14
Q

Antibodies to low incidence Antigen

What discrepancy?

A

Group 2

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15
Q

What is the remedy for Subgroup of A or B discrepancy in Group 2?

A

Lectins (Dolicus Biflorus)

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16
Q

“Bm” Antigen is an example of what group discrepancy?

A

Group 2

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17
Q

In acquired B phenomenone, E coli contains __________ that converts N-acetyl-D-galactosamine into D-galactosamine which which the individual may react to Anti __ resulting to ________ (Strong/Weak) reaction

A

N-acetylase
B
Weak

18
Q

If the patient has acquired B phenomenon, the results in the saliva has the same result in the blood

T or F

A

F

Changes in antigen only happens in the blood

19
Q

Remedy for Acquired B phenomenon?

A
  • Use saliva
20
Q

Acetic anhydride is a remedy for?

A

Acquired B phenomenon in Group 2 discrepancy

21
Q

This use for Reacylation of the surface molecule

A

Acetic anhydride

22
Q

Group 3 Discrepancy are ___________ abnormalities

A

PRotein and Plasma

23
Q

Inflammation increases Acute phase reactant which has __________ charge causing the RBCs to stack which is known as ________

A

Positive
Rouleaux formation

24
Q

Autocontrol uses _________ serum + ________ RBC

A

Patient
Patient

25
Q

Remedy for increased globulin content and Fibrinogen, and Plasma expander

A
  • Check for Rouleaux formation
  • Wash RBC (For forward typing only)
26
Q

In autoantibodies, there is no agglutination in the body but there is agglutination when extracted

T or F

A

T

27
Q

In autoantibodies, there is rouleax formation

T or F

A

F

No formation due to ANTIBODIES are the ones that sensitize the RBCs instead of Proteins

28
Q

What is the group discrepancy for Autoantibodies?

A

Group 3

29
Q

Remedy for Autoantibodies?

A

Warm the sample

30
Q

What are Group 4 Miscellaneous problems?

A

Polyagglutination
Antibodies against Acriflavine
Cold Reactive Antibody
Unexpected ABO isoagglutinins

(PAC U)

31
Q

What group discrepancy is this?
Anti A: 4+
Anti B: 0
KA: 0
KB: 1+
AC: 0

A

Group 1 discrepancy

32
Q

What group discrepancy is this?
Anti A: 4+
Anti B: 0
KA: 4+
KB: 4+
AC: 0

A

Group 2 Discrepancy
A2 / Subgroup of A

33
Q

What Group discrepancy is this?

Involves Remedy: Lectins such as Dolichus Biflorus

A

Group 2 (Subgroup A or B)

34
Q

What group discrepancy is this?

Patient has Kell
Anti A: 4+
Anti B: 4+
KA: 0
KB: 4+
AC: 0

A

Group 2 Discrepancy (Antibodies to Low incidence Ag due to the reagent has Anti K while the patient has Kell)

35
Q

What group discrepancy is this?

Patient ate contaminated food resulting to these results
Anti A: 3+
Anti B: 1+
KA: 0
KB: 4+
AC: 0

A

Group 2 Discrepancy (Acquired B phenomenon)

36
Q

Remedy for Antibodies to Low incidence Ag

A
  • Check for Reagent
37
Q

What group discrepancy is this?

Anti A: 4+
Anti B: 4+
KA: 1+
KB: 2+
KO: 2+
AC: 2+

A

Group 3 Discrepancy

38
Q

Anti A: 4+
Anti B: 4+
KA: 1+
KB: 2+
KO: 2+
AC: 2+

a. Check for Intestinal Infection
b. Check for patient’s cells
c. Check for patient’s age

A

b

39
Q

Anti A: 4+
Anti B: 1+
KA: 0
KB: 4+
KO: 0
AC: 0

a. Check for Intestinal Infection
b. Check for patient’s cells
c. Check for patient’s age

A

a

40
Q

Anti A: 4+
Anti B: 4+
KA: 0
KB: 0
KO: 0
AC: 0

a. Check for Intestinal Infection
b. Check for patient’s cells
c. Check for patient’s age

A

c

MTAP 2 Blood Banking Part 1 (18 decks)

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