4.1 ISBT 003 (P) Flashcards
Who discover P in 1927?
Landsteiner and levine
P is destroyed by enzyme
T or F
F
Enhance
Anti-Tja is composed of Anti P, P1, Pk
T or F
T
Anti Tja is a small “p” phenotype which compose P (-), P1 (-), and Pk (-)
T or F
T
Small “p” indicates the absence of P, P1, and Pk. This means antibodies are produce specifically Anti-Tja (Anti P, P1, Pk)
Anti Tja are naturally produce
T or F
F
After exposure
Anti-P1 discovered in P1 patient with _____________
Echinococcus granulosus
Patient infected with E. granulosus has a hytatid cyst that contains ___like substance which then pop and disperse these substance into the blood stream producing the Anti-P1
P1
Anti-P1 is a significant antibody
T or F
F
It is an interference since this may affect the compatibility testing
Fascioliasis (Bovine Liver fluke) and Bird handlers contains P1 antigen
T or F
F
Anti-P1
How to neutralized Anti-P1?
- Hydatic cyst
- Pigeon dropping
- Turtle dove egg white
These contains P1 ANTIGENS which helps combine with anti-P1, neutralizing it
Anti Tja is a potent hemolysin which causes?
Spontaneous abortion
Anti Tja was disovered from a patient with cancer that contains “P” system while the patient has small “p”. The patient creates Anti-p which destroys the cancer however the consequence of these is spontaneous abortion
T or F
T
Anti P is a warm reactive IgM autoAb
T or F
F
Cold reactive IgG
Anti P is seen in what type of hemolysis?
Paroxysmal cold hemoglobinuria
What Antibody has a Biphasic hemolysin?
Anti-P
