5-1 (done perman) Flashcards

1
Q

CCK and secretin is secreted by what organ

A

duodenum

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2
Q

CCK is released in response to 1

secretin ? 2

CCK and secretin signal for the release of 3

A

1-fats and proteins

2-stomach acid

3-pancreatic zymogen (inactive enzyme precursor)

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3
Q

name pancreatic zymogens (4)

activated by what

A

Trypsin[ogen] - enteropeptidase

Trypsin activates all below:
Chymotrypsin[ogen]

[Pro]Elastase

[Pro]Carboxy-peptidase A + B

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4
Q

AA transport into ENTEROCYTES (in intestine) is linked to what
-two categories

A

[Na] for single AA

H+ for di and tripeptides

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5
Q

protein turnover (replace old/misfolded)

RATE? (g/day)

A

400 g/day

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6
Q

what the dif bt essential and non essential AA

A

essential has to be obtained thru diet

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7
Q

list out your essential AA (there is MN)

A

Any help in learning these little molecules proves truly valuable

Arginine 
Histidine
Isoleucine
Lysine
Threonine
Leucine
Methionine 
Phenylalanine
Tryptophan
Valine
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8
Q

AA can be used for GNG or ketogenesis - how

A

deaminate AA

use their carbon skeleton

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9
Q

1 -> 2 -> serine -> cysteine

A

1 methionine

2 homocysteine

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10
Q

1 -> tyrosine

A

1 phenylalanine

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11
Q

What’s dif between glutamate and glutamine

A

mine - amino group

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12
Q

serine vs cysteine

A

cy - SH

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13
Q

SAM’s other name

A

AdoMet

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14
Q

1 what forms SAM

2 SAM function

A

1) methionine -> SAM

2) SAM donates carbon to substrates

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15
Q

”” transfers carbons in intermediate oxidation states

A

THF

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16
Q

histamine is a vasodilator or constrictor

A

dilator

17
Q

histamine mediates that kinds of rxn

A

allergic

18
Q

histamine is synthesized from what

A

histidine

19
Q

serontonin function

A

1 pain

2 sleep

20
Q

serontonin is synthesized from what

A

tryptophan

21
Q

creatine is formed from what

A

arginine and glycine

22
Q

what is a marker for muscle damage in the BLOOD

A

creatine kinase

23
Q

histamine, creatine, and serontonin are products of what rxn (mediated by what enzyme)

A

decarboxylation

mediated by pyridoxal phosphate

24
Q

”” are used for diagnosis of heart attack

A

myocardial isoforms

25
Q

failing kidney function INDICATOR

A

high serum creatinine

26
Q

INDICATOR of decreased muscle mass

INDICATOR of liver damage

A

low urine creatinine

liver-high AST (Aspartate aminotransferase) and high ALT (Alanine aminotransferase)

27
Q

how many ATP can you get from NADH

A

3 ATP

28
Q

most AA are broken down in what organ of body

however branched chain amino acids are degraded where 2

A

liver

2-muscle

29
Q

BCAA include what AA

A

isoleucine
valine
leucine

30
Q

function of glutamate dehydrogenase

A

deanimates glutamate, which frees nitrogen for urea cycle (in liver) or urine (in kidney)

read: but in rest of body, GD catalzyes the opposite rxn