4th Year Pharmacology Flashcards
when to stop OCP for major/ leg surgery?
4 weeks prior
can re-start 2 weeks post-surgery
warfarin in minor surgery
if INR <3.5 then can be done without stopping
warfarin in major ops
stop for 3-5 days pre-op, can convert to IV heparin or LMWH in interim
re-introducing warfarin post-op
warfarin is pro-thrombotic so give LMWH first
DOACs in surgery
low bleeding risk omit 24 hours prior, if high risk then 48 hours
what is the risk of operating on patients who have been on long-term steroids?
may not be able to mount a sufficient adrenal response to the stress of surgery
when should extra-steroid cover be considered in surgery?
when taking >5mg/d pred
who are aromatase inhibitors used in?
post-menopausal women only