(45) Hydrolytic Digestion Flashcards

1
Q

(Sites of hyrdolytic Digestion)

1-2. Name the two types of digestion (where they occur) - plus what is digested at each site

A
  1. luminal digestion (carbohydrate, protein, lipid)
  2. brush border digestion (in intestine) (maltose, peptides, monoglycerides)
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2
Q

(Carbohydrate Digestion/Absorption)

  1. what enzyme resides in the mouth and non-sepcially cleaves shizz
  2. what enzyme works on trehalose (from mushrooms)? to make what?
  3. lactose?
  4. sucrose?
  5. Starch, glycogen, sucrose, fructose, lactose, trehalose are all made into what?
A
  1. amylase
  2. trehalase, glucose
  3. lactase, glucose and galactose
  4. sucrase, glucose and fructose
  5. monosaccharides
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3
Q

(Signs of Carbohydrate malassimilation)

1-4. What are the four signs?

A
  1. fluid diarrhea
  2. weight loss
  3. borborygmus (rumbling due to movement in intestines - bacteria producing gassss)
  4. flatulence
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4
Q

(Disorders Characterized by Carbohydrate Metabolism)

1-2. Luminal Maldigestion

3-6. brush border maldigestion

  1. membrane malabsorption
A
  1. exocrine pancreatic insufficiency
  2. small intestinal bacterial overgrowth
  3. exocrine pancreatic insufficiency
  4. small intestinal bacterial overgrowth
  5. small intestinal mucosal disease
  6. disaccharaidase deficiency
  7. small intestinal mucosal disease
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5
Q

(Protein Digestion/Absorption)

  1. What digests in stomach? comes from what which is activated by what?
  2. Does bulk of digestion occur in small intestine? what converts trypsinogen to trypsin? What does trypsin go on to do?
  3. What are the proteins broken down into?
  4. can oligopeptides be directly absorbed? when is this not a good thing?
A
  1. pepsin - from pepsinogen which is made into pepsin via low pH
  2. yes; enterokinase; convert other zymogens to active forms
  3. amino acids, di and tri peptides, oligopeptides
  4. yes; frog-skin neurotoxins
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6
Q

1-2. What are the two signs of protein malassimilation?

A
  1. weight loss
  2. +/- diarrhea

(may only get weight loss)

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7
Q

(Take a look at this)

note that the first two are the same as previous except for

food allergy/sensitivity reactions

and last three are all different

listen 3/15/2013 8 AM from for this slide… I’m sorry - sick and all you know

A
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8
Q

(Lipid Digestion/Absorption)

  1. Triglycerides (the mian one) are digested via what three enzymes? into what?
  2. cholesterol is digested via what enzyme? made into what?
  3. phospholipid?
A
  1. lingual, gastric, and pancreatic (main one in animals) lipases; monoglyceride, fatty acid, and glycerol
  2. cholesterol ester hyrdolase; cholesterol and fatty acid
  3. phospholipase A2; lysolechitin and fatty acid
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9
Q

(Signs of Lipid Malassimilation)

1-3 what are they?

A
  1. steatorrhea (excess fat in feces)
  2. malodrous feces
  3. weight loss
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10
Q

here we go again…

gastrinoma - tumor of gastrin producing cells - luminal lipid maldigestion - goes to pancreatic acinar cels to get them to secrete zymogens - also binds parietal cells and gets them to secrete acid into stomach - so too much acid means ulcers

A
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11
Q

(Prerequisites for Fermentative Digestion)

1-4. What are the four?

A
  1. reservoir - retention of ingesta, microbes
  2. oxygen content - anaerboic environment
  3. acidity - suitable pH range (6-7)
  4. removal mechanism - of end products
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12
Q

(Proximal Colon)

  1. Consists of what parts of colon?
  2. what type of muscle movement
  3. what type of peristalsis?
  4. mixining of what?
  5. extraction of what?
A
  1. ascending and transverse
  2. segmentation
  3. anti-peristalsis
  4. contents
  5. water
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13
Q

(Distal Colon)

  1. What part of colon?
  2. What purpose does it serve?
  3. what type of movement?
  4. defecation
A
  1. distal colon
  2. stoarge
  3. massive movement
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14
Q

(Oxygen Content - Anareobic Environment)

  1. Colonic bacteria - strict aerobes or anaerobes?

(Oxygen introduced in food and water)

  1. diffuse across what?
  2. used by what?
  3. serves as a what?
  4. fermentation produces what?
A
  1. anaerobes
  2. foregut epithelium
  3. facultative anaerobes
  4. electron acceptor
  5. metabolic H2
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15
Q

bicarbonate main thing used to offset this - in ruminants and in domestic

A
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16
Q

note that Ac- is acetate and HAc is acetic acid

takes place in distal gut (proximal colon) of domestic, rumen, pregastric fermentation of kangaroo

A
17
Q

(Fermentative Digestion Endpoints)

  1. Carbohydrates become what?
  2. proteins?
  3. lipids?
  4. microbial cells?
A
  1. VFA + CO2 + CH4
  2. ammonia + keto acids
  3. fatty acids + proprionate
  4. anaerobes
18
Q

check this out

A
19
Q

(Effects of SCFA on GII Function)

SCFA contribute to what foru things?

A
  1. intestinal mucosa
  2. fluid/electrolyte balance
  3. energy metabolism
  4. colonic motility
20
Q

(Sucession ecology of GI Tract)

basically cat’s have more (10^9) bacteria in gut than dogs (10^5)

A