4.3 Meiosis and Mutations Flashcards
Explain how crossing over results in variation.
Crossing over- during Meiosis 1, bits of chromatids swap over to contain the same genes but different sections of alleles
Explain how independent segregation results in variation
Independant segregation of homologous chromosomes, random process of which chromosomes from each parent separate into which daughter cell (one from mother one from father)
Explain how random combination leads to variation in meiosis
random process in which gametes combine to form a zygote
Summarise the process of meiosis 1
meiosis 1
- homologous chromosomes pair up
-chromatids cross over- to contain different alleles
- One chromosome from each homologous pair ends up in each cell
Summarise the process meiosis 2
Meiosis 2
-sister chromatids separate to opposite sides of the cell by microtubules and the production of 4 daughter cells
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What happens in prophase 1?
chromatin condenses into chromosomes
homologous chromosomes pair up to form homologous chromosome pairs
Separates homologous chromosomes
What happens in metaphase 1?
Homologous chromosome pairs line up along centre of the cell and microtubules attach
What happens in anaphase 1?
Microtubules seperate homologous chromosome pairs
What happens in telephase 1?
The nuclear envelope reappears, two cells are formed
What is the difference between meiosis 1 and meiosis 2?
The first division of meiosis, which reduces the number of chromosomes in a cell by half. results in 2 daughter cells with half the number of chromosomes.
meiosis 2- pair of sister chromatids separated. 4 haploid cells produced
How can you calculate the number of different zygotes with different paternal and maternal chromosome combinations?
2^n where n is the number of chromosome pairs
How can you calculate the number of different gametes with different paternal and maternal chromosome combinations?
Describe what. a mutagenic agent is and identify some possible mutagenic agents?
Increases chances of mutation such as UV light and viruses
What is a non-disjunction effect and how does it occur?
chromosomes fail to separate, occurs in prophase 1