3.5 Anti-anemic + Hematopoietic Stimulating Drugs

Question 1

What is required for Erythropoiesis? (4)

Answer 1

• Erthropoietin (EPO)
• Folate
• B12
• Iron

Question 2

What is primarily used to compensate for medical conditions resulting in low erythrocyte production?

Answer 2

Recombinant EPO therapy

Question 3

What can be used to classify anemia?

Answer 3

Erythrocyte MVC (mean corpuscular volume)

Question 4

What can occur with the treatment of iron deficiency anemia with iron?

Answer 4

Can decrease absorption of:

• Quinolone
• Tetracycline antibiotics

Question 5

Iron therapy is contraindicated following …

Answer 5

Chronic Transfusion Therapy for Thalassemia Anemia

Question 6

What are 2 beneficial treatments for Sickle Cell Anemia?

Answer 6

• EPO
• Folate

Question 7

Use of EPO in treatment of Sickle Cell Anemia can increase what levels in these pts?

Answer 7

Hemoglobin F

Question 8

What drug is an iron chelator?

Answer 8

Deferoxamine

Question 9

What drug is useful in preventing Hemosiderosis in Sickle Cell Anemia and Thalassemia pts transfusion therapy?

Answer 9

Deferoxamine

Question 10

What can Pophyria attacks be triggered by?

Answer 10

• UV light
• Variety of anesthetics that may be used for dental procedures

Question 11

How can Macrocytic B12 Deficient Anemia be distinguished from Folate Deficient Anemia?

Answer 11

• Presence of neurological symptoms
• Increaseed serum levels of methylmalonic acid

Question 12

What is predominantly used to treat Neutropenia?

Answer 12

Myeloid Growth Factor

Question 13

What can be used to treat Thrombocytopenia?

Answer 13

Thrombopoietic Growth Factors