3.2 ATP: Energy Currency of the Cell Flashcards
ATP:
Adenosine Triphosphate
ATP directly supplies energy that powers cellular function
Universal energy “currency”
ATP helps power;
- Mechanical Work
Beating cilia, muscle mvmt, chromosome mvmt - Transport Work
Pumping substances across membranes against
their concentration gradient - Chemical Work
Providing chemical potential energy for non-
spontaneous, endergonic rxns
(e.g., proteinsynthesis and DNA replication)
ATP Hydrolysis and Free
Energy
Specifically the crowded, negatively charged phosphate groups repel one another and
weaken the bonds holding them together
These bonds can be easily broken by Hydrolysis
(adding H2O) to release energy
Hydrolysis breaks off one phosphate group,
forming ADP and an inorganic phosphate (Pi) and Energy
Energy Coupling
using energy released from one reaction to drive another reaction
Phosphorylation
attaching a phosphate group to another organic molecule
results in the molecule gaining FREE ENERGY and becoming more reactive
Energy Coupling requires an enzyme to…
bring ATP close to the reactant molecule in an endergonic reaction
the enzyme has specific sites where ATP and the reactant molecule bind
Most work carried out in a cell is dependent on…
phosphorylation for energy
Regeneration of ATP
Cells make ATP by combining ADP + Pi
This requires FREE ENERGY (thus is endergonic)
Energy needed for ATP synthesis comes from
the exergonic breakdown of complex molecules in the
food we eat (carbs, fats, and proteins)
At least 10 million times every second,
ATP molecules are hydrolyzed and resynthesized in a typical cell
The continued breakdown and resynthesis of ATP is called the
ATP Cycle
The ability for ATP to
couple to so many
different endergonic
reactions gives ATP its
“universal” characteristic
ATP is the Universal Energy
Currency
The ability to assemble
ATP using energy from a
variety of food molecules ensures
all vital reactions in a cell
can be performed