303 This Year Flashcards
- Translocation with which of the Y-linked gene to one of the X chromosomes is the case in most testicular disorder of sex development (DSD), known as 46, XX male syndrome?
A. SRY, sex (determining) region Y chromosome
B. CFTR. CF transmembrane conductance regulator
C. AR, androgen receptor
D. HBB, hemoglobin subunit beta
E. AZF, azoospermia factor region
A. SRY, sex (determining) region Y chromosome
- Which one below is caused by mutation in the cystic fibrosis (CFTR) gene?
A. Congenital absence of vas deferens (CAVD)
B. SRY -negative 46.XX
C. Down syndrome
D. Polycyctic ovary syndrome (PCOS)
E. 46.XX/47.XYY mosaicism
A. Congenital absence of vas deferens (CAVD)
- Which of the following is an important precursor of placental steroids?
A. Inhibin
B. Maternal LDL cholesterol
C. Activin
D. Arachidonic acid
E. Carnitine
B. Maternal LDL cholesterol
- A student is nervous for a big exam and is breathing rapidly, what do you expect out of the following?
A. Metabolic Acidosis
B. Metabolic Alkalosis
C. Respiratory Acidosis
D. Respiratory Alkalosis
E. Simultaneous respiratory and metabolic acidosis
D. Respiratory Alkalosis
Which of the following enzymes convert circulating testosterone to biologically active compo-
unds?
A. ATPase
B. 178-hydroxysteroid dehydrogenase type II
C. 11B-hydroxylase
D. 5a-reductase
E. Adipose tissue lipoprotein lipase
D. 5a-reductase
- After meals, pregnant women enter the starved state more rapidly because of increased consumption of glucose and amino acids by the fetus. Choose the wrong answer.
A. Plasma glucose levels fall rapidly
B. Plasma amino acids levels fall rapidly
C. Plasma insulin levels fall rapidly
D. Glucagon and placental lactogen levels rise
E. Lipolysis and ketogenesis are inhibited
E. Lipolysis and ketogenesis are inhibited
- What hormone keeps the uterine lining thick in preparation for pregnancy?
A. Inhibins
B. Testosterone
C. Estrogen
D. Progesterone
E. Activins
C. Estrogen
- If a male does not enter puberty sometime in his teens, his doctor might prescribe which medi-cation(5)?
A. Estrogen and progesterone
B. Progesterone
C. Growth hormone
D. Testosterone
E. Growth hormone and follicle stimulating hormone
Testosterone
- Artery of the ductus deferens is a branch of which artery listed below?
A. Abdominal aorta
B. Superior vesical artery
C. External iliac artery
D. Renal artery
E. Median sacral artery
B. Superior vesical artery
- The androgen receptor is a member of the steroid thyroid superfamily. It elicits its activity by interacting with which of the following?
A. Specific androgen response elements in the DNA of target genes
B. A Nuclear membrane protein located in the nuclear pores
C. A glycoprotein on the membrane of the lysosomes
D. G-Protein in the plasma membrane
E. CAMP
A. Specific androgen response elements in the DNA of target genes
- Which of the following muscle is the continuation of cremasteric muscle in the scrotum?
A. External oblique abdominis muscle
B. Transversus abdominis muscle
C. Fascia transversalis
D. Internal oblique abdominis muscle
E. Pyrimadalis muscle
D. Internal oblique abdominis muscle
- Which of the following structure is not neighbour of posterior surface of the right kidney?
A. Right twelfth rib
B. Right psoas major
C. Right quadratus lumborum
D. Right genitofemoral nerve
E. Right ilioinguinal nerve
D. Right genitofemoral nerve
- A 39 years old woman is admitted to the hospital with pelvic pain. Radiographic examination reveals a benign tumor on the left ovary. An ovariectomy is performed and the ovarian vessels
vessels are ligated?
are ligated. Which of the following structures has the highest risk of injury when the ovarian
A. Uterine artery
B. Vaginal artery
C. Ureter
D. Internal pudendal artery
E. Pudendal nerve
C. Ureter
- A 64 years old man is admitted to the emergency department due to increasing difficulty in urinating over a period of several months. Physical examination reveals prostatic hypertrophy.
After several unsuccessful attempts to catheterize the penile urethra, the urologist orders drainage of the urinary bladder by the least invasive procedure, avoiding entry into the peritoneal cavity or the injury of any major vessels or organs. Which of the following spaces needs to be traversed by the needle to reach the bladder?
A. Ischioanal fossa
B. Perineal body
C. Retropubic space of Retzius
D. Superficial perineal cleft
E. Deep perineal pouch
C. Retropubic space of Retzius
- Which of the following structure is located in the deep perineal space (pouch) of male?
A. Ischiocavernosus
B. Bulb of penis
C.Bulbospongiosus
D.Bulbourethral glands
D.Bulbourethral glands
- Which of the following is the narrowest part of the male urethra?
A. Prostatic sinus
B. Internal urethral orifice
C. External urethral orifice
D. Posterior of navicular fossa
E. Bulbar fossa
C. External urethral orifice
- Which of the following is not one of the anterior division branch of the internal iliac artery?
A. Inferior vesical artery
B. Middle rectal artery
C. Internal pudendal artery
D. Inferior gluteal artery
E. Superior gluteal artery
E. Superior gluteal artery
- A 46 years old woman is admitted to the hospital with severe uterine bleeding. Radiographic examination reveals uterine fibroids. A uterine artery embolization is performed. Which of the following arteries will supply collateral circulation to the uterus?
A. External iliac
B. Inferior mesenteric
C. Ovarian
D. Internal pudendal
E. Superior mesenteric
C. Ovarian
- Radiographic studies of a 42-vear-old woman reveal that she has a vulvar malignancy involving the clitoris. Removal of all affected lymph nodes would be indicated to avoid spread of this cancer. Which are the first lymph nodes to filter the lymphatic drainage of the involved
area?
A. Superficial and deep inguinal lymph nodes
B. Internal iliac lymph nodes
C. Paraaortic lymph nodes
D. Presacral lymph nodes
E. Popliteal lymph nodes
A. Superficial and deep inguinal lymph nodes
A 30-year-old industrial worker presents with anxiety. She is heavily exposed to oral and inhaled arsenic at her workplace, and she has just found out that she is 4 weeks pregnant. She has done some research and is concerned about the element affecting a structure termed “mesonephric duct? in the ferus.
20. Which of the following structures might be affected in the fetus?
A. Distal convoluted tubules
B. Major urinary calyces
C. Urinary bladder
D. Penile part of the urethra
E. Navicular fossa of the urethra
B. Major urinary calyces
A 30-year-old industrial worker presents with anxiety. She is heavily exposed to oral and inhaled arsenic at her workplace, and she has just found out that she is 4 weeks pregnant. She has done some research and is concerned about the element affecting a structure termed “mesonephric duct? in the fetus
- During a routine second-trimester ultrasound, she finds out that the sex of the fetus is male.
Unfortunately, the radiologist also reports that the mesonephric duct has actually undergone severe developmental defects. Which of the following organs should still be normal in the new-
bom?
A. Epididymis
B. Vas deferens
C. Seminal vesicles
D. Prostate gland
E. Ejaculatory duct
D. Prostate gland
- A 6-year-old boy is admitted to the hospital because of a palpable mass located external to the aponeurosis of the external oblique. Radiographic examination reveals that the mass is an ectopic testis, classified as interstitial. Failure of normal development of which of the following embryologic structures is responsible for ectopic testis?
A. Gubernaculum
B. Processus vaginalis
C. Genital tubercle
D. Seminiferous cords
E. Labioscrotal swellings
A. Gubernaculum
- Which molecules have an activating role in the differentiation of the gonads towards the ovary?
WTI
Sf1
SOX9
WNT4
role
No role
No role
No role
Has role
- Which of the following is correct about the Sertoli cell?
I. Synthesis of insulin-like protein 3 (INSL3)
IL. Basally located, clear, oval nucleus with a large, centrally positioned nucleolus
II.
The lateral cell membranes form occluding junctions for blood-testis barrier
IV.
Synthesis of activin
V. Contains crystals of Reinke
VI. Synthesis and release of anti-mullerian hormone
A.I-III- V. VI
B.I-I-IV- V
C. II- II- V. VI
D.II- III-IV-VI
E.I-II-III-IV
D.II- III-IV-VI
- Which of the following cells are shown by arrows in the micrograph? Hair band purple
A. Primary spermatocyte
B. Secondary spermatocyte
C. Leydig cell
D. Sertoli cell
E. Elongated spermatid
D. Sertoli cell
- Which of the following organs is shown in the micrograph? Hollow 4 leaf
A. Ureter
B. Ductus epididymis
C. Urethra
D. Ductus deferens
E. Ductus efferent
D. Ductus deferens
- Which of the followings is correct for epididymis?
A. Corpora amylacea is found in epididymis
B. It contains tubuloalveolar gland
C. Fructose is secreted by epididymis
D.Glycerophosphocholine is secreted by epididymis
E. Fertilization promoting peptide is secreted by epididymis
D.Glycerophosphocholine is secreted by epididymis
- Which of the following best describes the function of the renal structure indicated by the red arrows in the image?
A. Bulk reabsorption of solutes
B. Erythropoietin production
C. Formation of the corticopapillary gradient
D. Urine-concentrating mechanisms
E. Urine-diluting mechanisms
C. Formation of the corticopapillary gradient
- The image below is used to explain the kidneys’ ability for tubuloglomerular feedback in response to increased renal arterial pressure. Which of the sites labeled 1-4 are correctly identified as the sites where a change is sensed and the site primarily respond to the change?
31
- A patient experiences unexplained low blood clotting, and a problem in reabsorption is eventually considered. Under normal conditions, which segment labeled on the image below (1-7) reabsorbs the largest percentage o Inad of magnesium?