300-309 Flashcards
https://drive.google.com/open?id=0B8uJUY-tie8GUWpFWFRrbTlJdTQ
https://drive.google.com/open?id=0B8uJUY-tie8GeFBpOUlGeUhLSnM
Function as barriers, separating the contents of cells and organelles
PM
Asymmetric sheetlike structures consisting of an outer and an inner
surface.
■ Outer: More carbohydrates (glycoproteins, glycolipids) and
glycosphingolipids.
■ Inner: More phospholipids.
Plasma mem.
PM
Selectively permeable, enabling only small, nonpolar molecules (O2,
CO2, etc) and water to easily pass.
■ Contain lipids, proteins, and carbohydrates in varying ratios.
PM
Lipids and integral proteins generally interact noncovalently, allowing molecules
to move freely within the membrane
;ipids
Form an amphipathic lipid bilayer suspended in water with hydrophilic
head groups (on the outer and inner surfaces) and hydrophobic tail groups
(on the inside of the bilayer).
Phospholipids
■ Phosphoglycerides
Phosphatidylcholine (lecithin)
Phosphatidylethanolamine (cephalin)
Phosphatidylglycerol (cardiolipin)
■ Phosphatidylserine
■ Phosphatidyinositol
■ Sphingomyelin
Types of plasma membrane lipids:
Glycosphingolipids
■ Galactoceramide
■ Glucosylceramide
■ Gangliosides
■ Cholesterol and other steroids
PM lipids
Function as receptors, transport channels, enzymes, antigens, and other
structural components
proteins
Integral: Amphipathic proteins that are embedded within either one or
both (traverse the entire membrane) portions of the lipid bilayer.
■ Peripheral: Proteins that weakly bind to hydrophilic head groups on
the inner or outer membrane surfaces.
Two types of plasma membrane protein
Attach to proteins and lipids only on the external surface of cell membranes
CARB
Uniport:
Transport of a single molecule in both directions
.■ Coupled:
Transport of one molecule depends on the presence of another
(different) molecule.
Transports molecules in the same direction.
Transports molecules in opposite directions.
Symport vs. ■ Antiport:
https://drive.google.com/open?id=0B8uJUY-tie8GMVFzdWk2QkE0NWc
https://drive.google.com/open?id=0B8uJUY-tie8GZFd5NHRMVmtYTVk
Facilitative bidirectional transporters of glucose
Glucose Transporters
GLUT-1:
Erythrocytes, brain
GLUT-2:
Liver, pancreas
GLUT-3:
Neurons