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Clinical Chemistry 2 > 3. Tumor Markers > Flashcards

3. Tumor Markers Flashcards

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1
Q

Prostate tumor marker(s)

A

PSA

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2
Q

Non-cancerous reasons for AFP >1000 ug/L

A

Pregnancy

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3
Q

ALP is a tumor marker for these 3 types of cancer

A

Lung
Liver
Ovarian

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4
Q

Testicular tumor marker(s)

A

Beta-HCG

AFP

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5
Q

Which germ cell tumor?

High AFP

A

Yolk sac tumor

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6
Q

Ovarian tumor marker(s)

A 
CEA
CA 125
beta-HCG
ALP
AFP
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7
Q

AFP and HCG in teratoma

A

Both normal

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8
Q

Which germ cell tumor?

High HCG

A

Choriocarcinoma

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9
Q

Lymphoproliferative disorders (MM, Waldenstrom’s lymphoma) is monitored by this tumor marker

A

B2-microglobulin

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10
Q

AFP and HCG in choriocarcinoma

A

AFP norm

HCG increased

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11
Q

CA 15-3 is most useful for staging this type of cancer

A

Breast

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12
Q

Protease enzyme tumor marker

A

PSA

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13
Q

AFP and HCG in yolk sac tumor

A

AFP increased

HCG norm

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14
Q

4 non-seminomas (type of germ cell tumor)

A
  • Yolk sac tumor
  • Choriocarcinoma
  • Embryonal carcinoma
  • Teratoma
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15
Q

AFP is a tumor marker for these 2 types of cancer

A

Liver

Ovarian

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16
Q

Stomach tumor marker(s)

A

CEA

CA 19-9

17
Q

Biomarker mainly used for colorectal cancer

A

CEA

18
Q

AFP can be increased in those with what 3 conditions?

A
  • Hepatocellular carcinoma
  • Germ cell carcinoma
  • Pregnancy
19
Q

Breast tumor marker(s)

A

CEA

CA 15-3

20
Q

Lung tumor marker(s)

A

CEA
ALP
CA 19-9

21
Q

Tumor made up of several different types of tissue

A

Teratoma

22
Q

Useful for colorectal and pancreatic carcinomas

A

CA 19-9

23
Q

Thyroid tumor marker(s)

A

Thyroglobulin

24
Q

CA 19-9 can be used to diagnose which cancers?

A
  • Lung
  • Liver
  • Stomach
  • Pancreatic
  • Colorectal
25
Q

Follow-up for positive FOBT/FIT test

A

Colonscopy

26
Q

Most common type of cancer - formed by epithelial cells

A

Carcinomas

27
Q

Colorectal tumor marker(s)

A

CEA
CA 19-9
FOBT
FIT

28
Q

AFP and HCG in embryonal carcinoma

A

Both increased

29
Q

Which germ cell tumor?

High AFP and high HCG

A

Embryonal

30
Q

Cancer formed in bone and soft tissues (muscle, fat, blood vessels, lymph vessls, fibrous tissue)

A

Sarcomas

31
Q

Useful for monitoring ovarian carcinomas

A

CA 125

32
Q

What does ‘TNM’ in TNM staging system stand for?

A

Tumor, Node, Metastasis

33
Q

3 PROTEIN tumor markers

A

B2-microglobulin
Immunoglobulins
Thyroglobulin (TG)

34
Q

Pancreatic tumor marker(s)

A

CEA

CA 19-9

35
Q

Liver tumor marker(s)

A

AFP
ALP
CA 19-9

36
Q

Aggressive type of testicular cancer w/ spread to lungs, bones, brain

A

Choriocarcinoma

37
Q

Useful for staging breast cancer

A

CA 15-3

38
Q

3 ‘screening’ tumor markers

A

PSA
FOBT
FIT

Clinical Chemistry 2 (15 decks)

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