18. Instrument and Method Evaluation Flashcards
1
Q
The lowest actual concentration at which the precision of measurement is still LESS than the allowable error
A
LOQ
2
Q
What are the 2 categories of systematic errors?
A
- Proportional systematic error
- Constant error
3
Q
3 terms that describe aspects of the minimum analytical sensitivity of a method
A
- Limit of blank (LOB)
- Limit of detection (LOD)
- Limit of quantitation (LOQ)
4
Q
Lamp, cuvette, calibration changes, picric acid coating cuvette are all examples of what type of error?
A
Systematic errors
5
Q
How are proportional systematic errors assessed?
A
Recovery studies
6
Q
Compares patient sample results between new method and comparative method
A
Correlation studies
7
Q
Errors that result from biases are introduced by what 3 ways?
A
- Instrumental bias
- Method bias
- Human bias
8
Q
4 approaches to analyzing comparison of method data
A
- Correlation coefficient
- T-test statistics
- Linear regression statistics
- Estimation of Total Error and allowable total error
9
Q
How are ‘constant errors’ assessed?
A
Interference studies
10
Q
Bias is assessed by..?
A
Correlation studies
