16. Trace Elements, Atomic Absorption Spectrophotometry

Question 1

At what state can elements absorb radiation?

Answer 1

Ground state

Question 2

Disease where copper is deficient and one where copper is in excess

Answer 2

Deficient - Menkes disease

Excess - Wilsons disease

Question 3

Increase of this compound in urine is highly suggestive of lead toxicity

Answer 3

Aminolevulinic acid (ALA)

Question 4

Essential or non-essential? Antimony

Answer 4

Non-essential

Question 5

Sample of choice for zinc analysis?

Answer 5

Plasma

Not serum b/c zinc is 5-15% higher due to contamination from cells during clotting and spinning

Question 6

Why is a morning specimen recommended for zinc analysis?

Answer 6

Concentrations of zinc are affected by circadian and postprandial fluctuations

Question 7

What is acrodermatitis enteropathicia associated with?

Answer 7

Zinc deficiency

Question 8

Toxin that can disrupt the production of heme

Answer 8

Lead

Question 9

Essential or non-essential?Cobalt

Answer 9

Essential

Question 10

Lipophilic form of mercury

Answer 10

Methylmercury

Question 11

Lead poisoning may cause this to be seen in a peripheral blood film

Answer 11

Basophilic stippling

Question 12

Essential or non-essential? Cadmium

Answer 12

Non-essential

Question 13

Can cross BBB and placenta

Answer 13

Lead

Question 14

Essential or non-essential? Molybdenum

Answer 14

Essential

Question 15

This disease is diagnosed by green-gold Kayser-Fleischer rings in the cornea

Answer 15

Wilsons disease

Question 16

Essential or non-essential? Aluminum

Answer 16

Non-essential

Question 17

Mercury has a high affinity for ____________ in proteins

Answer 17

sulfhydryl groups

Question 18

Trace element sample is held upright at room temperature for _____ mins to allow to clot

Answer 18

30 mins

Question 19

Essential or non-essential? Selenium

Answer 19

Essential

Question 20

Copper deficiency may be misdiagnosed as?

Answer 20

Myelodysplastic syndrome