3 DISORDER OF CORNEA Flashcards
Which of the following is not belong to superficial lesions
- Filaments
- Pannus
- Vascularization
Vascularization
Which of the following is not belong to superficial lesions
- Punctate epithelial erosions
- Lipid Deposition
- Subepithelial infiltrates
Lipid Deposition
Which of the following is not belong to superficial lesions
- Ulceration
- Punctate epithelial keratitis
- Epithelial edema
Ulceration
Which of the following is not belong to superficial lesions
- Infiltrates
- Superficial punctate keratitis
- Filaments
Infiltrates
Which of the following is not belong to deep lesions
- Infiltrates
- Superficial punctate keratitis
- Ulceration
Superficial punctate keratitis
Which of the following is not belong to deep lesions
- Seidel test
- Descemetocele
- Punctate epithelial keratitis
Punctate epithelial keratitis
Which of the following is not belong to deep lesions
- Lipid Deposition
- Epithelial edema
- Breaks in Descemet Membrane
Epithelial edema
generally an early sign of epithelial compromise
- Subepithelial infiltrates
- Punctate epithelial keratitis
- Punctate epithelial erosions
Punctate epithelial erosions
Granular, opalescent, swollen epithelial cells, with focal intraepithelial infiltrates
- Subepithelial infiltrates
- Punctate epithelial keratitis
- Punctate epithelial erosions
Punctate epithelial keratitis
tiny subsurface foci of non-staining inflammatory infiltrates
- Subepithelial infiltrates
- Punctate epithelial keratitis
- Punctate epithelial erosions
Subepithelial infiltrates
is a non-specific term describing any corneal epithelial disturbance
- Filaments
- Superficial punctate keratitis
- Epithelial edema
Superficial punctate keratitis
strands of mucus admixed with epithelium, attached at one end to the corneal surface
- Filaments
- Superficial punctate keratitis
- Epithelial edema
Filaments
subtle cases may manifest with loss of normal corneal luster
- Filaments
- Superficial punctate keratitis
- Epithelial edema
Epithelial edema
is a feature of chronic ocular surface irritation or hypoxia
- Pannus
- Superficial neovascularization
- Epithelial edema
Superficial neovascularization
describes superficial neovascularization accompanied by degenerative subepithelial change extending centrally from the limbus
- Pannus
- Superficial neovascularization
- Epithelial edema
Pannus
are focal areas of acute stromal inflammation composed of inflammatory cells, and cellular and extracellular debris including necrosis
- Ulceration
- Vascularization
- Infiltrates
- Folds
Infiltrates
refers to tissue excavation associated with an epithelial defect
- Ulceration
- Vascularization
- Infiltrates
- Folds
Ulceration
in Descemet membrane
- Ulceration
- Vascularization
- Infiltrates
- Folds
Folds
may follow chronic inflammation with leakage from corneal new vessels
- Seidel test
- Lipid Deposition
- Breaks in Descemet Membrane
- Descemetocele
Lipid Deposition
may be due to corneal enlargement (Haab striae in infantile glaucoma) or deformation
- Seidel test
- Lipid Deposition
- Breaks in Descemet Membrane
- Descemetocele
Breaks in Descemet Membrane
usually only develops when the ocular defences have been compromised
- FUNGAL KERATITIS
- BACTERIAL KERATITIS
BACTERIAL KERATITIS
is rare in temperate countries but is a major cause of visual loss in tropical and developing countries
- FUNGAL KERATITIS
- BACTERIAL KERATITIS
FUNGAL KERATITIS
is a phylum of obligate intracellular one-celled parasites previously thought to be protozoa but recently reclassified as fungi
- MICROSPOROIDAL KERATITIS
- HERPES SIMPLEX KERATITIS
MICROSPOROIDAL KERATITIS
developed with a cuboidal capsule and has a linear double-stranded DNA genome
- MICROSPOROIDAL KERATITIS
- HERPES SIMPLEX KERATITIS
HERPES SIMPLEX KERATITIS
HSV
without previous viral exposure, usually occurs in childhood and is spread by droplet transmission, or less frequently by direct incolation
- Primary infection
- Recurrent infection
Primary infection
HSV
reactivation in the presence of cellular and humoral immunity
- Primary infection
- Recurrent infection
Recurrent infection
yellow-white densely suppurative infiltrate
- Candida keratitis
- Filamentous keratitis
Candida keratitis
Agreyor yellow-white stromal
infiltrate with indistinct fluffy
margins.
- Candida keratitis
- Filamentous keratitis
Filamentous keratitis
dendritic or geographic keratitis
associated with ACTIVE VIRUS replication.
- EPITHELIAL KERATITIS
- DISCIFORM KERATITIS
EPITHELIAL KERATITIS
dendritic or geographic keratitis
associated with ACTIVE VIRUS replication.
- EPITHELIAL KERATITIS
- DISCIFORM KERATITIS
EPITHELIAL KERATITIS
dendritic or geographic keratitis
associated with ACTIVE VIRUS replication.
- EPITHELIAL KERATITIS
- DISCIFORM KERATITIS
EPITHELIAL KERATITIS
It may be active HSV infection of keratocytes or endothelium, or a hypersensitivity reaction to
viral antigen in the cornea.
- EPITHELIAL KERATITIS
- DISCIFORM KERATITIS
DISCIFORM KERATITIS
This rare condition is thought to
result from active viral replication within the stroma, though immune-mediated inflammation plays a
significant role.
- NECROTIZING STROMAL KERATITIS
- HERPES ZOSTER OPHTHALMICUS (HZO)
NECROTIZING STROMAL KERATITIS
The varicella-zoster virus (VZV) causes both chicken pox (varicella) and shingles (herpes
zoster).
- NECROTIZING STROMAL KERATITIS
- HERPES ZOSTER OPHTHALMICUS (HZO)
HERPES ZOSTER OPHTHALMICUS (HZO)
VZV belongs to the same subfamily of the herpes virus group as the HSV and the two viruses are morphologically identical but antigenically
distinct.
- NECROTIZING STROMAL KERATITIS
- HERPES ZOSTER OPHTHALMICUS (HZO)
HERPES ZOSTER OPHTHALMICUS (HZO)
A prodromal phase precedes the
appearance of the rash.
- Acute shingles
- Interstitial keratitis
- Cogan syndrome
Acute shingles
an inflammation of the corneal stroma without primary involvement of the epithelium or endothelium.
- Acute shingles
- Interstitial keratitis
- Cogan syndrome
Interstitial keratitis
a rare systemic autoimmune vasculitis characterized by intraocular inflammation and
vestibulo auditory dysfunction
- Acute shingles
- Interstitial keratitis
- Cogan syndrome
Cogan syndrome
ubiquitous free-living
protozoa commonly found in soil, fresh or brackish water and the upper respiratory tract.
- Acanthamoeba
- Onchocerciasis
Acanthamoeba
‘river blindness’
- Acanthamoeba
- Onchocerciasis
Onchocerciasis
caused by infestation with the
parasitic helminth Onchocerca
volvulus
- Acanthamoeba:
*
Onchocerciasis:
caused by infestation with the
parasitic helminth Onchocerca
volvulus
- Acanthamoeba
- Onchocerciasis
Onchocerciasis
probably caused by a hypersensitivity reaction against staphylococcal exotoxins and cell wall proteins
- Marginal keratitis
- Phlyctenulosis
Marginal keratitis
usually a self-limiting disease
presumed delayed hypersensitivity reaction to
staphylococcal antigen; the most common systemic association is rosacea.
- Marginal keratitis
- Phlyctenulosis
Phlyctenulosis
a rare, idiopathic disease
characterized by progressive circumferential peripheral, stromal ulceration with later central spread.
- Mooren ulcer
- Terrien marginal degeneration
Mooren ulcer
uncommon idiopathic
thinning of
the peripheral cornea. Presentation is usually after the 4th decade with initially asymptomatic peripheral corneal lesions
- Mooren ulcer
- Terrien marginal degeneration
Terrien marginal degeneration
occurs when there is loss of the trigeminal innervation to the
cornea resulting in partial or complete anaesthesia
- NEUROTROPHIC KERATOPATHY
- EXPOSURE KERATOPATHY
NEUROTROPHIC KERATOPATHY
is the result of incomplete lid closure (lagophthalmos). present on blinking or gentle lid closure, but absent on forced lid closure.
- NEUROTROPHIC KERATOPATHY
- EXPOSURE KERATOPATHY
EXPOSURE KERATOPATHY
refers to the spectrum of ocular disease caused by lack of vitamin A, and is a late manifestation of
severe deficiency.
- XEROPHTHALMIA
- CORNEAL ECTASIAS
XEROPHTHALMIA
a progressive disorder in which the cornea assumes a conical shape secondary to stromal thinning and protrusion.
- KERATOCONUS
- KERATOGLOBUS
Keratoconus
an extremely rare congenital condition in which the entire cornea is abnormally thin.
- KERATOCONUS
- KERATOGLOBUS
KERATOGLOBUS
The hallmark of _____ is central or paracentral stromal thinning, accompanied by apical protrusion and irregular astigmatism.
- Keratoconus
- Acute hydrops
- Keratoconus
Presentation is typically during puberty with unilateral impairment of vision due to progressive myopia and astigmatism, which subsequently
becomes irregular.
- Keratoconus
- Acute hydrops
keratoconus