15.6 KHURANA OF EYELIDS Flashcards
These include; simple papilloma, naevus, angioma, haemangioma, neurofibroma and sebaceous adenoma.
- Benign tumours
- Pre-cancerous conditions
- Malignant tumours
Benign tumours
These are solar keratosis, carcinoma in situ and xeroderma pigmentosa.
- Benign tumours
- Pre-cancerous conditions
- Malignant tumours
Pre-cancerous conditions
Commonly observed tumours include squamous cell carcinoma, basal cell carcinoma, malignant melanoma and sebaceous gland adenocarcinoma.
- Benign tumours
- Pre-cancerous conditions
- Malignant tumours
Malignant tumours
are the most common benign tumours arising from the surface epithelium.
- Papillomas
- Xanthelasma
Papillomas
These are creamy-yellow plaque-like lesions which frequently involve the skin of upper and lower lids near the inner canthus
- Papillomas
- Xanthelasma
Xanthelasma
represents lipid deposits in histiocytes in the dermis of the lid.
- Papillomas
- Xanthelasma
Xanthelasma
common type of birthmark that are usually red or purple.
- Haemangioma
- Neurofibroma
Haemangioma
These may be superficial and bright red in colour (strawberry naevus) or deep bluish or violet in colour.
- Capillary haemangioma
- Naevus flammeus (port wine stain)
- Cavernous haemangiomas
Capillary haemangioma
It may occur pari passu or more commonly as a part of Sturge-Weber syndrome.
- Capillary haemangioma
- Naevus flammeus (port wine stain)
- Cavernous haemangiomas
Naevus flammeus (port wine stain)
It consists of dilated vascular channels and does not grow or regress like the capillary haemangioma.
- Capillary haemangioma
- Naevus flammeus (port wine stain)
- Cavernous haemangiomas
Naevus flammeus (port wine stain)
developmental venous anomaly and usually occur after first decade of life.
- Capillary haemangioma
- Naevus flammeus (port wine stain)
- Cavernous haemangiomas
Cavernous haemangiomas
It consists of large endothelium-lined vascular channels and usually does not show any regression.
- Capillary haemangioma
- Naevus flammeus (port wine stain)
- Cavernous haemangiomas
Cavernous haemangiomas
Lids and orbits are commonly affected in neurofibromatosis (von Recklinghausen’s disease).
- Haemangioma
- Neurofibroma
Neurofibroma
The tumour is usually of plexiform type
- Haemangioma
- Neurofibroma
Neurofibroma
occur as nonpigmented protrusions with a keratin filled central crater.
- Keratoacanthomas
- Naevi
Keratoacanthomas
common cutaneous lesions that arise from the arrested epidermal melanocytes .
- Keratoacanthomas
- Naevi
Naevi
located at the epidermis/dermis
- Junctional naevi
- Dermal naevi
- Compound naevi
Junctional naevi
are flat, brown in appearance
- Junctional naevi
- Dermal naevi
- Compound naevi
Junctional naevi
“brown appearance, flat”
located within the dermis, are elevated lesions which may not be visibly pigmented.
- Junctional naevi
- Dermal naevi
- Compound naevi
Dermal naevi
“no visible pigment, elevated”
share features of junctional and dermal naevi
- Junctional naevi
- Dermal naevi
- Compound naevi
Compound naevi
though a common lesion of sun exposed skin is relatively uncommon on the eyelids.
- Actinic keratosis
- Xeroderma pigmentosa
Actinic keratosis
Characteristic features of this autosomal recessive
(AR) disease are:
• Progressive cutaneous pigmentation resulting from
damage on exposure to natural sunlight.
• Bird-like facies is typical of this condition.
• Predisposition to develop lid tumours
- Actinic keratosis
- Xeroderma pigmentosa
Xeroderma pigmentosa
Predisposing factors include increasing age, white skin, sun exposure, xeroderma pigmentosa and basal
cell naevus syndrome.
- Basal cell carcinoma
- Squamous cell carcinoma
Basal cell carcinoma
It forms the second commonest malignant tumour
of the lid. It is commonly arises from the lid margin (mucocutaneous junction) in elderly patients
de novo or from pre-existing lesion such as actinic
keratosis, Bowen’s disease and radiation dermatosis.
- Basal cell carcinoma
- Squamous cell carcinoma
Squamous cell carcinoma
Risk factors include sun exposure, radiation, fair skin, injury or other irritative insults.
- Basal cell carcinoma
- Squamous cell carcinoma
Squamous cell carcinoma
“sun exposure”
There is a male predilection.
- Basal cell carcinoma
- Squamous cell carcinoma
Squamous cell carcinoma
It is a rare tumour arising from the meibomian glands
(western literature)
- Sebaceous gland carcinoma
- Malignant melanoma (Melanocarcinoma)
Sebaceous gland carcinoma
Clinical features. It usually presents initially as a nodule (which may be mistaken for a chalazion), more frequently on the upper eyelid. Which then grows to form a big growth
- Sebaceous gland carcinoma
- Malignant melanoma (Melanocarcinoma)
Sebaceous gland carcinoma
is a rare tumour of the lid (less than 1% of all eyelid lesions).
- Sebaceous gland carcinoma
- Malignant melanoma (Melanocarcinoma)
Malignant melanoma (Melanocarcinoma)
It may arise from a pre-existing naevus, but usually arises de novo from the melanocytes present in the skin.
- Sebaceous gland carcinoma
- Malignant melanoma (Melanocarcinoma)
Malignant melanoma (Melanocarcinoma)