2Dp1-Transcription Flashcards
KEY TERM - Gene expression
the process of reading the information stored within a gene to create a functional product (Normally a protein)
KEY TERM - Transcription
Where a sequence of DNA is used a template for polymerase to create a complementary sequence of mRNA.
KEY TERM - what is pre-mRNA?
the immediate product of transcription-requieres modifications before it undergoes translation.
KEY TERM - mRNA
RNA molecules that are produced during transcription and carry genetic information from the nucleus to the ribosomes.
Transcription has -
3 phases
stage one -
Initiation - Unwinding or unzipping (figurative) of the the DNA in the location of the gene being transcribed. Then RNA Polymerase begins catalysing the process.
Stage two
Elongation - The process where pre-mRNA strand is being created as the RNA polymerase moves along the gene site.
Stage three -
Termination - The end of the transcription where the new mRNA molecule is detached and the DNA ‘zips’ back up again.
What is RNA Polymerase?
An enzyme that catalyzes or speeds up the reaction that leads to the creation of mRNA
What is RNA processing?
The introns are cut out-leaving the enzyme only with Exons. Then they add a 5’ Methyl-G cap, and a 3’ Poly-A tail. They are added to protect the pranscript and help export it from the nucleus to the ribosome.
Where does transcription occur?
Inside the nucleus