252 Pharmacology - Antitubercular Drugs Flashcards
Define aerobic.
Requiring oxygen for the maintenance of life.
What are granulomas?
Small nodular aggregations of inflammatory cells (e.g., macrophages, lymphocytes); usually characterized by clearly delimited boundaries, as found in tuberculosis.
What are interferon gamma release assays (IGRAs)?
Surrogate markers of Mycobacterium tuberculosis infection; indicate a cellular immune response to M. tuberculosis.
What is isoniazid?
The primary and most commonly prescribed antitubercular drug.
What is multi-drug resistant tuberculosis?
Tuberculosis that demonstrates resistance to two or more drugs.
What is a slow acetylator?
An individual with a genetic defect that causes a deficiency in the enzyme needed to metabolize isoniazid, the most widely used tuberculosis drug.
