(25) restrictive

Question 1

Which way does the shift occur in restricitive lung disease

Answer 1

Left

Question 2

FEV/FVC in restrictive?

Answer 2

Increased

Question 3

What do you see in Idiopathic Pulm Fibrosis

Answer 3

Usual Interstitial Pneumonia histology

Question 4

Buzzword for IPF

Answer 4

honeycomb lungs

Question 5

Microscopic IPF

Answer 5

microscopic honeycomning

fibroblast foci

Question 6

Coal workers pneumoconiosis location

Answer 6

Upper lungs

Question 7

What is Caplan syndrome

Answer 7

Coal workern pnemo

Rheumatoid arthritis

Question 8

Who gets silicosis

Answer 8

mining
foundry
stell worker
sandblasting

Question 9

What does silica do

Answer 9

causes oxygen radical formation which leads to IL-1 and necrosis

Question 10

What has egg shell calcification

Answer 10

Silicosis

Question 11

Histology of silicosis

Answer 11

Hyalinized collagen concentric

Question 12

Who gets berrylosis

Answer 12

aerospace

Question 13

What happens in berryilosis

Answer 13

Th1 response that invovled interferon gamma and IL-2

Question 14

What gene is in berryilosis

Answer 14

HLA-DPB1

Question 15

What is seen in berryilosis

Answer 15

non caseating granulomas

Question 16

What do you see pleural plaques in

Answer 16

Asbestosis

Question 17

What does asbestosis have in it

Answer 17

asbestos bodies (iron)

Question 18

Where is asbestosis located

Answer 18

lower lung/periphery

Question 19

What is seen in sarcoidosis

Answer 19

non caseating granuloma

upper lobes

skin/joint/eye lesions

Question 20

What causes sarcoidosis

Answer 20

Macophage and dendritic activation that make giant cells.

IL2 and IL15
Inf gamma
IL6 and IL8

Question 21

Microscopic sarcoidosis

Answer 21

Well formed granuloma

Asteroid body
Schaumann body
calcium oxalate crystals

Question 22

What do you see in hypersensitivity pneumonitis

Answer 22

ground glass appearance

Question 23

Restrictive disease on DLCO

Answer 23

DLCO decreased