(24) Obstructive Flashcards

1
Q

COPD major risk factor

A

smoking

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2
Q

COPD genetic deficiency

A

Alpha 1 antitripsin deficiency

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3
Q

FEV/FVC in Obstructive

A

Lowered

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4
Q

What happens in obstructive

A

Increased FRC and RV

Decreased IC

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5
Q

what do you see in COPD

A

hyperinflated lungs and flattened diaphragm

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6
Q

What emphysema is in smokers

A

Centrilobular (Centriacinar)

Upper lobe

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7
Q

What emphysema is not associated with smokers

A

Panacinar

alpha 1 antitrypsin deficiency

Lower lung

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8
Q

When do you say chronic bronchitis

A

Persistent cough for 3 consecutive months in 2 years

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9
Q

What do you see histologically in chronic bronchitis

A

inflammatory cells

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10
Q

What is reversible

A

Asthma

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11
Q

Asthma patho

A
TH2
CD4
IL4
IL5
IL10

Eosinophils

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12
Q

What happens in asthma

A

smooth muscle hyperplasia

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13
Q

What is characteristic of asthma

A

eosinophils

Curschmann’s spirals

Carcot Leyden Crystals

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14
Q

What area is bronchiectisis more common

A

lower lung

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15
Q

Types of Bronchiectisis

A

Cylindrical
Varicose
Saccular

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16
Q

FEV1/FVC ratio in bronchiectisis

A

Reduced

17
Q

Bronchiectisis CT

A

dilated airways with secretions

18
Q

Alergic Bronchopulmonary Aspergillosis

A

Central bronhiectasis