(24) Obstructive Flashcards
COPD major risk factor
smoking
COPD genetic deficiency
Alpha 1 antitripsin deficiency
FEV/FVC in Obstructive
Lowered
What happens in obstructive
Increased FRC and RV
Decreased IC
what do you see in COPD
hyperinflated lungs and flattened diaphragm
What emphysema is in smokers
Centrilobular (Centriacinar)
Upper lobe
What emphysema is not associated with smokers
Panacinar
alpha 1 antitrypsin deficiency
Lower lung
When do you say chronic bronchitis
Persistent cough for 3 consecutive months in 2 years
What do you see histologically in chronic bronchitis
inflammatory cells
What is reversible
Asthma
Asthma patho
TH2 CD4 IL4 IL5 IL10
Eosinophils
What happens in asthma
smooth muscle hyperplasia
What is characteristic of asthma
eosinophils
Curschmann’s spirals
Carcot Leyden Crystals
What area is bronchiectisis more common
lower lung
Types of Bronchiectisis
Cylindrical
Varicose
Saccular