(22) respiratory viral Flashcards by Taylor Spry

Q

How does infection start in respiratory virus

A

epithelial cell receptor attachment

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Q

Paramyxoviridae structure

A

SS RNA -

has RNAdep RNA polyerase

envelope w/ spikes

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Q

Paramyxoviridae glycoproteins

A

Hemagglutinin

Neruaminidase

Fusion protein

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Q

Paramyxoviruses glycoproteins

A

HN, F

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Q

Morbilliviruses glycoproteins

A

H, F

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Q

RSV glycoproteins

A

F

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Q

What does F do

A

mediates fusion between virus and cell membrane

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Q

Patamyxoviridae replication site

A

cytoplasmic

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Q

Parainfluenza type kids get first then following order

A

3, 1, 2, 4

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Q

what % for herd immunity

A

96%

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Q

What causes pneumoviridae

A

RSV then parainf 3, 1,2,4

immune complex IgA in children

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Q

what has to happen to hemagluttinin

A

must be cleaved to be active

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Q

What is antigenic drift

A

epidemics

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Q

What is antigenic shift

A

Pandemics. mix of 2 viruses

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Q

what helps with mucus in viruses

A

Neuraminidase

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Q

Influ type B

A

younger

No aspirin bc Reye syndrome

Guillain burre

Q

What blocks uncoating

A

amantidine and rimantadine

Q

What inhibits viral RNA synthesis

A

Ribavirin

Q

What blocks neuraminidase

A

Zanamivir

Peramivir

Oseltamivir

prevent budding

Q

What prevents cleavage of cell cap

A

Baloxavir

Marboxil

Q

What is IIV

A

inactivated influenza

Q

Fluzone?

A

high dose for old ppl

Q

Flublock vaccine

A

18 and up H isolated

Q

What makes IgA and IgG

A

Intranasal vaccine

Rhinovirus setup

ss RNA +

Coccacies A and B | Echo

cold rinitis

Rhinoviruses are

acid labile

What do rhinoviruses cause

mostly upper respiratory viruses

Coronaviridae structure

helical SS RNA + envelope (PEPLOMERS)

What does SARS cause

upper and lower respiratory tract

how did corona virus start

fish market to yuumans