23. Oral Mucosal Infections Flashcards
[T/F] C. Albicans is dimorphic
True
- exist in yeast or hyphae forms
- conversion to hyphae form is associated w disease progression
[T/F] Candida spps are opportunistic pathogens
True. ‘Disease of the Diseased’ of the
- very young, very old, very sick, very dry
- when host defenses are compromised
[T/F] Candida albicans is not commensal
False
- actually normal oral commental in 45-60%
- also commensal in vagina
What does the Germ tube test test for?
C. Albicans & C. Dubliniensis
- germ tube formation inoculated in serum at 37 degrees celsius
- only these 2 species will convert to hyphae from from yeast form
- will notice germ tubes (outgrowth/pouching produced by spores)
What are some conditions that can arise due to C. Albicans?
- Angular chelitis in denture wearers
- Denture stomatitis
- White vaginal discharge w itch
- Oropharyngeal/pseudomembranous candidiasis (oral thrush)
Which medication is a good topical anti-fungal to combat against C. Albicans?
Nystatin
(issa polyene)
How does oropharyngeal/pseudomembranouse candidiasis (oral thrush) present?
- white patches on tongue that can be wiped off to revel erythmatous surface
- associated w HIV
- yeast & pseudohyphae (under microscope)
What is the difference between angular chelitis and denture stomatitis?
Angular chelitis refers to the inflammation at the angles of the mouth/lip area
Denture stomatitis occurs usually under the base of upper dentures (esp well fitted ones)
- but related, when u see angular chelitis, also gotta look under denture to check for denture stomatitis
Denture-induced stomatitis occurs more often on which arch?
Upper dentures
- especially well fitted ‘perfect’ ones
- saliva cannot wash through => perfect for candida to proliferate
- lower dentures usually dh cuz got saliva flow
Angular cheilitis can be due to..
- Angular cheilitis
- Staph aureus
Name the the bacterial infections that can occur in the oral mucosa?
- Syphilis
- ANUG
- Tuberculosis
- Actinomycosis
- Osteromyelitis of the jaw
What is ANUG?
Acute Ulcerative Necrotising Gingivitis
What is the tx for ANUG?
- oral debridement, improve OHI
- H2O2 or chlorhexidine irrigation
- penicillin or metronidazole
What is Actinomycosis?
- chronic sinus tract infection
- sulphur granules is not actually sulphur, just looks like it
- issa yellow purulent material
- not a fungal infection
Definition:
Chronic, suppurative infective bacterial disease of the upper neck, perioral areas and/or jaws w interconnecting draining sinus tract containing sulphur granules
Cervicofacial actinomycosis presents most commonly in the..
Mandible
What bug causes Actinomycosis?
Actinomyces israelii
- anaerobic gram +ve bacteria
How is Actinomycosis treated?
- surgical drainage of abscess
- prolonged administration of AB
-> penicillins, erythromycin/clindamycin - clindamycin would be rlly good for dent conditions cuz 1. Penetrates bone 2. Targets anaerobes BUT it causes CDAD, so we only reserve it for serious infections
Why do pxs who get IV drip likely get infection by S. Aureus?
S. Aureus resides on skin
- when needle pokes through skin
- S. Aureus can get in
