22 Flashcards
acinar cells of pancreas make
digestive enzymes that break down carbs, proteins and fat
— activate pancreatic zymogens
enterokinase- found in the duodenum activates trypsingen into trypsin, and then trypsin activates everyone else
common cause of pancreatitis in dogs
hyperlipidemia- hyperthyroid, cushings, DM
dietary indiscretion
high fat meals
common cause of pancreatitis in cats
idiopathic
triaditis
what is triaditis in cat
pancreatitis
cholangitis (GB inflam)
IBD
(common duct for pancrease and GB)
how to diagnose pancreatitis in dogs
non specific clinical signs: V, anorexia, abdominal pain, ∓ LI diarrhea, ↓BP, icterus, pleural effusion
CBC chem UA- not specific
Xray- increased pancreatic angle
US
PLI- pancreatic lipase immunoreactivity
* > 400
* snap cPL >200 abnormal
treatment for pancreatitis in dogs
supportive care
* nutrition- small low fat meals or feeding tubes
* antiemetics
* pain meds
* IV fluids
* ∓antibiotics
how to diagnose pancreatitis in cat
harder- very non specific signs
vomiting and pain only in 40% of cases
usually chronic
fPLI
US
how to treat pancreatitis in cats
- supportive care
- nutritional- feeding tube, no withholding of food
- anti nausea, pain meds
- antibiotics- possible cholangitis- clindamycin, choramphenicol, metro
what causes exocrine pancreatic insufficiency (EPI) in dogs
pancreatic acinar cell atrophy
* immune mediated
* progresses as they get older
what causes exocrine pancreatic insufficiency in cats
chronic pancreatitis
clinical signs of EPI in dogs
weight loss
diarrhea- alot and fatty
very hungry
- german shepherd
- young adults
diagnosis of EPI is by
fasted TLI
cobalamin (Vit B12) also prob low cause pancreas makes intrisic factor needed to absorb it
how to treat EPI
pancreatic enzyme supplementation
* long term
* can be $$
* Vit B12 can also help
