16 Flashcards
liver failure cholesterol is —, biliary obstruction cholesterol is —
low
high
LPL works by
brings FFA into fat cells and stores it
- downregulated in starvation
HSL works by
breaks TG into FFA
* breaks down fat
* stimulated by NE, EPI, steroids, glucagon, thyroxine
* inhibited by insulin
insulin will do what to HSL
stops it from breaking down fat/TG into FFA
what happens to FFA after they are released from fat cells
move to hepatocyte
liver values with hepatic lipidosis in cats
high ALP
normal or mildly ↑ GGT
treatment for hepatic lipidosis
- feeding tubes
- supportive care- IV fluids, antiemetics
- treat underlying disease
- 60% survive- long recovery time
how to diagnose neutrophilic cholangitis
- biopsy shows neutrophils within lumen or epithelium of bile duct
- ∓↑ AST,ALT
- hyperbilirubinemia
- bile cytology and culture
cholangitis= bile duct inflammation
found in area of liver around triad: portal vein, hepatic artery, bile duct
what causes neutrophilic cholangitis
ascending bacterial infection from GI tract into the bile duct
how to treat neutrophilic cholangitis
based off liver biopsy and culture or bile cytology and culture
* usually gram - and anaerobes from ascending infection from GI tract
* Penicillin works well
how to treat lymphocytic cholangitis
- base off of liver biopsy and culture
- maybe immune-mediated?, usually longer duration, insidious onset
- treat with prednisolone or ursodiol
why might cats with cholangitis also have pancreatitis and IBD
share duct for pancreas and gallbladder
* ascending infection
how to diagnose lymphoma in liver in cat
cytology
biopsy
- hard to tell small cell lymphoma
- treat with chemo
mast cell tumors in liver of cats usually
are also in the spleen
- cause liver failure and gastric ulcers
