204 MSK - Disease & Pharmacology

Question 1

Muscle relaxants

Answer 1

Neuromuscular blockers

• Nondepolarizing - D-tubocurarine
• Depolarizing - Succinylcholine

Spasmolytics
- Benzodiazepines - diazepem

2 receptors

• Acetylcholine receptor
• Ryanodine receptors

Question 2

Spasmolytics

Muscle relaxants

Answer 2

Benzodiazepines - diazepem

• GABA A agonist

Question 3

Butyrylcholinesterase (BCHE) deficiency

Answer 3

Prolonged apnoea after use of succinylcholine and mivacurium

Question 4

Malignant Hyperthermia

Answer 4

Severe reaction from succinylcholine with halothane

Question 5

Bone infections (2)

Answer 5

Osteomyelitis

Septic arthritis

Question 6

Muscle infections (2)

Answer 6

Pyomyositis

Tetanus

Question 7

Osteomyelitis

Answer 7

Inflammatory process accompanied by bone destruction caused by an infecting microorganism

骨髓炎

Question 8

Septic arthritis

Answer 8

Inflammation of the joint space caused by an infection

敗血性關節炎

Question 9

Pyomyositis

Answer 9

Infection of skeletal muscle

Question 10

Difference between necrotizing fasciitis and myonecrosis

Answer 10

Necrotizing fasciitis involves skin or mucosa breach

Question 11

Inflammatory arthritis

Answer 11

Autoimmune disease

Clearly defined group of conditions where there is joint or tendon inflammation

Question 12

Presentation of rheumatoid arthritis

Answer 12

Pain and stiffness in small joints, usually hands & feet

類風濕關節炎

Question 13

Disease-modifying anti-rheumatic drugs (DMARDs)

Answer 13

Methotrexate
- does not provide analgesia but they reduce inflammation

Hydroxychloroquine - exception - does not prevent joint erosion