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MBBS > 204 MSK - Biochemistry > Flashcards

204 MSK - Biochemistry Flashcards

1
Q

Bone vs cartilage

A

Bone
- nonflexible & rigid

Cartilage
- flexible & non-rigid

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2
Q

3 types of cartilages

A

Differ mainly in the composition of ECM

  1. Hyaline cartilage
  2. Fibrocartilage
  3. Elastic cartilage
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3
Q

Production and removal of extracellular matrix (ECM) by?

A

Chondrocytes

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4
Q

Chondrodysplasia

A

Impairment in the function of the growth plate

軟骨發育不良

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5
Q

Osteoarthritis

A

Impairment in the function of articular cartilage

骨關節炎

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6
Q

Cartilage formation markers

A

Type II collagen C-propeptide

CS-neoepitope (aggrecan)

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7
Q

Cartilage degradation markers

A

KS (Keratan sulfate) (aggrecan)

COMP

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8
Q

In young healthy adult resorption and formation are ______ such that bone mass remains constant

A

balanced

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9
Q

Hormones regulating bone metabolism

A

Parathyroid hormone (PTH) - bone resorption
Calcitonin - bone formation
1,25-dihydroxyl cholecalciferol - bone formation

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MBBS (28 decks)

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