2010 Module Exam Flashcards
What Type of endothelium found in Splenic sinus?
A. Discountinous endothelium
B. Discontinues basal lamina
B. Discontinues basal lamina
A 56 years old male presented to the ER with 60 mins duration of severe chest pain and dizziness. Also he is unresponsive to sublingual nitrate. What is the best cardiac biomarker will be found in blood sample at this time?
A. Myoglobin
B. Ck MB
C. Troponin I
A. Myoglobin
Which one of the following most likely will develop secondary hypertension?
A 27 years old male with BP = 170/99 and abdominal bruits
What’s the mechanism of action of Nitroglycerine ?
Increase cGMP
What most likely would be the effect of a drug that blocks K+ channels during repolarization?
A. Prolonged AP, Prolonged phase 4
B. prolonged AP, prolonged phase 2
A. Prolonged AP, Prolonged phase 4
What would be effected on ECG if you give a patient a drug that affects Na+ Fast Channels?
A. ST Segment
B. RR interval
C. QRS Complex
B. RR interval
or C
What’s the mechanism of action of Verapmil?
Ca Channels blocker
Which of the following studies is used to study specific genes in Kuwaiti families?
SNP Linkage Studies
Question about asking the patient about what they think of their disease and how to plan out a strategy before treating it?
(Sorry We don’t remember the question exactly!) P.S. They asked about the stage before this step)
What reduces the risk of pulmonary edema in a patient with long standing left ventricular heart failure?
A. increased pulmonary capillary pressure
B. increased heart rate
C. improved lymphatic system
D. increased blood volume
B. increased heart rate
or
C. improved lymphatic system
If we inject a patient with Sailne .. what will happen? (We don’t remember the question)
A. increase plasma concentration of ADH
B. Increase in Blood Pressure
B. Increase in Blood Pressure
Which of the following Factors has protease activity and is released from kidneys when the renal blood perfusion reduced?
Renin
An IV drug abuser was admitted to the hospital. He was diagnosed with IE , chest x- ray showed multiple lung abscess and blood culture showed +ve gram bacteria. What most likely would be the cause?
S.Aureus
A 92 years old female presented with collapsing pulse on the radial artery, and mid- Diastolic murmur. What is the Blood Pressure?
140/60
(I think she has Aortic Regurgitation so DBP must be low, and she is 92 years old so Compliance is reduced leading to increase SBP)
(*collapsing pulse, AKA aortic regurgitation)
Which of the following factors is the most contributing in movement of blood to inferior vena cava: A. intrathoracic negative pressure B. elastic lamellae C. longitudinally arranged muscle fibers D. presence of valves E. internal elastic lamellae
A. intrathoracic negative pressure
or
C. longitudinally arranged muscle fibers
What helps aorta to maintain the blood pressure?
internal elastic lamina
What is the prominent histological feature seen in Brachiocephalic artery?
Elastic lamalle
A middle aged female presented with History of Rhematic heart disease. What valvular disease will be associated with her condition?
Small Vegetations on the mitral valve (History of RHD!Calcification and Aortic Stenosis?)
Which of the following will confirm Dilated HF?
Displaced apex Laterally
What is the mechanism of action of a drug that inhibits bile duct absorption?
high density LDL receptors
Which of the following mechanisms mediate vasoconstriction when blood pressure is increased?
Myogenic Regulation
What mechanism causes vasodilation of muscle arteries during exercise?
Active Hyperemia
A 55 years old male presented with episodes of Syncope, what is the cause? A. 1st Degree AV Block B. 2nd Degree AV Block C. 3rd Degree AV Block D. Ventricular Arrhythmia E. Atrial Fibrillation
C. 3rd Degree AV Block
In 3rd Degree Block, Purkinje fibers are the pacemaker of the heart HR = 40-25 bpm
“In This range as we decrease HR, CO decreases → Syncope”
What drug causes consipitation as a side effect?
Verapmil
What is the mechanism that causes increase CO in anemia?
decrease Afterload
Anemia→low RBCs→low Viscosity→reduce SVR→reduce Afterload
What is the mechanism of action of Spirolactone?
binding to Aldestrone receptors inhibiting its effect
What is the mechanism of action of Nitroglycrine?
increase cGMP
A patient presented with Mitral stenosis and heart failure, what is the best drug combination?
Beta-blockers, Duertics, Digoxin
(Mitral Stenosis means that the ventricle needs more time to fill, so we give them Beta-blocker to reduce HR, therefore, increase diastolic time i.e. filling time increase)
A patient presented with Left Ventricular and septum Hypertrophy. Post-mutorm biopsy showed disarray?
Hypertrophic cardiomyopathy
Which of the following drugs dissociate slowly from Na channels and have no effect on Action Potential?
Flecaidine
Which of the following mechanism causes clubbing?
Capillary beds expansion
Which of the following drugs binds to Activated Na channels only?
Quinidine
Week 6 case arrhythmia- Valsava Manouver?
parasympathetic activation
How does the body response for increasing intracranial pressure?
increase Blood pressure and decrease HR
A mother in her 10th week of pregnancy, she had 3 children with severe congenital heart disease, and she want to check for her fetus. What test would you ask for?
A. Amionotic Fluid Aspirate
B. Chorionic Villi sample
B. Chorionic Villi sample (less than 12 weeks)
Which of the following drugs will not help a patient with angina perctuis?
A. Diuretics
B. Digioxin
A. Diuretics
Digioxin makes it WORSE!
A patient came to the ER complaining of episodes of chest pain on exertion, and he never experienced these episodes during rest. which of the following tests would you ask for?
Exercise ECG
A 63 years old male suffering from chest pain on exertion is diagnosed with classical angina pectoris. What drug is given to rapidly relieve the effect of the acute attack? A. Nitroglycrine B. Dobutamine C. Aspirin D. Verapamil E. Captopril
A. Nitroglycrine