201 Flashcards
Central Nervous System (CNS)
consists of the brain and spinal cord
The peripheral nervous system (PNS)
consists of all nervous tissue outside the CNS. Components of the PNS include nerves and sensory receptors.
Nervous system divisions
- Nervous system is dived into CNS and PNS
- CNS receives input for the sensory branch of the PNS, interprets is and then out puts signals to the motor brand of the PNS
PNS divisions
- is divided into Sensory and Motor divisions
- Motor division is dived into somatic and autonomic
- autonomic is dived into sympathetic and parasympathetic
The PNS is divided into a sensory (afferent) division and a motor (efferent) division.
- The sensory division conveys sensory input into the CNS from sensory receptors.
- The motor division conveys motor output from the CNS to effectors (muscles and glands).
The efferent (motor) division of the PNS is further subdivided into a somatic nervous system and an autonomic nervous system.
- somatic nervous system (conveys motor output from the CNS to skeletal muscles only)
- autonomic nervous system (conveys motor output from the CNS to smooth muscle, cardiac muscle, and glands).
The autonomic nervous system in turn is divided into a sympathetic division, parasympathetic division, and enteric plexuses.
The enteric plexuses in the wall of the digestive canal regulate the smooth muscle and glands of the digestive canal
The nervous system helps maintain homeostasis and integrates all body activities.
it does this by sensing changes (sensory function), interpreting them (integrative function), and reacting to them (motor function).
Nervous tissue consists of
neurons (nerve cells) and neuroglia.
Neurons have the property of electrical excitability
and are responsible for most unique functions of the nervous system: sensing, thinking, remembering, controlling muscle activity, and regulating glandular secretions.
Most neurons have three parts.
1-The dendrites are the main receiving or input region
2-The cell body, Integration occurs in the cell body, which includes typical cellular organelles.
3-the Axon, responsible for output which propagates nerve impulses toward another neuron, a muscle fiber, or a gland cell.
Synapses
the site of functional contact between two excitable cells. Axon terminals contain synaptic vesicles filled with neurotransmitter molecules.
slow axonal transport and fast axonal transport
systems for conveying materials to and from the cell body and axon terminals.
On the basis of their structure, neurons are classified as
- multipolar,
- bipolar,
- unipolar or pseudounipolar.
Neurons are functionally classified as
- sensory (afferent) neurons,
- motor (efferent) neurons,
- interneurons
Sensory neurons carry sensory information into the CNS.
Motor neurons carry information out of the CNS to effectors (muscles and glands).
Interneurons
located within the CNS between sensory and motor neurons.
Neuroglia
support, nurture, and protect neurons and maintain the interstitial fluid that bathes them.
Neuroglia in the CNS consist of
- astrocytes
- oligodendrocytes
- microglial cells
- ependymal cells
Neuroglia in the PNS consist of
- Schwann cells
- satellite cells.
Two types of neuroglia produce myelin sheaths:
Oligodendrocytes myelinate axons in the CNS, and Schwann cells myelinate axons in the PNS.
White matter consists of aggregates of myelinated axons
gray matter contains cell bodies, dendrites, and axon terminals of neurons unmyelinated axons, and neuroglia.
In the spinal cord, gray matter forms an H-shaped inner core that is surrounded by white matter.
In the brain, a thin, superficial shell of gray matter covers the cerebral and cerebellar hemispheres
Neurons communicate with one another
- using graded potentials, which are used for short-distance communication only
- nerve impulses, which allow communication over long distances within the body.
The electrical signals produced by neurons and muscle fibers rely on four kinds of ion channels:
- leak channels
- ligand-gated channels
- mechanically gated channels
- voltage-gated channels.
Leak channels
- Gated channels that randomly open and close.
- Found in nearly all cells, and dendrites, cell bodies, and axons of all types of neurons.
Ligand-gated channels Gated channels
- open in response to binding of ligand (chemical) stimulus.
- found on dendrites of some sensory neurons such as pain receptors and dendrites and cell bodies of interneurons and motor neurons.
Mechanically gated channels
- open in response to mechanical stimulus (such as touch, pressure, vibration, or tissue stretching).
- found on Dendrites of some sensory neurons such as touch receptors, pressure receptors, and some pain receptors.
Large nerve fibers
transmit impulses faster than small ones do
Which of the following cell types can conduct action potentials?
1) smooth muscle cells
2) cardiac muscle cells
3) neurons
4) neuroglia
5) skeletal muscle cells
all the above
Which of the following cell types can produce action potentials when stimulated?
1) smooth muscle cells
2) cardiac muscle cells
3) neurons
4) neuroglia
5) skeletal muscle cells
1,2,3,5
Which one of the following is NOT found in the central nervous system?
a. myelinated fibers
b. unmyelinated fibers
c. neurolemma
d. oligodendrocytes
e. astrocytes
C neurolemma is not part of the CNS
How is the resting membrane potential of -70mv (millivolts) best interpreted?
the inside of the fiber is 70mv more negative than the outside
The sodium pump:
actively transports sodium out of the cell
During the absolute refractory period a second action potential response can be produced:
never
A large number of nerve fibers running together within the central nervous system is referred to as a:
tract
gray matter contains mostly
neuron cell bodies and synapses
Cerebrospinal fluid is found between the:
pia and archnoid
Transmission across a chemical synapse is always in the same direction
true
A spinal puncture places the needle tip in the:
subarchnoid space
The anterior gray columns contain:
cell bodies of motor neurons
: reflex arc
is the simplest unit capable of detecting a stimulus and causing a response
The vital centers for control of heart, respiration and blood pressure are located in the:
medulla oblongata
The major control systems for balance and posture in the body as well as muscular coordination are located in the:
cerebellum
The most important central mechanism for temperature regulation is contained in the:
hypothalamus
corpus callosum
is the nerve fibers that connect the Hemispheres of the cerebrum
A resting membrane potential exists across the plasma membrane of excitable cells that are unstimulated (at rest).
The resting membrane potential exists because of a small buildup of negative ions in the cytosol along the inside surface of the membrane, and an equal buildup of positive ions in the extracellular fluid along the outside surface of the membrane.
A typical value for the resting membrane potential of a neuron is −70 mV.
A cell that exhibits a membrane potential is polarized.
The resting membrane potential is determined by three major factors:
(1) unequal distribution of ions in the ECF and cytosol;
(2) inability of most cytosolic anions to leave the cell;
(3) electrogenic nature of the Na+/K+ ATPases.
Graded Potentials
- A graded potential is a small deviation from the resting membrane potential that occurs because ligand-gated or mechanically gated channels open or close.
- A hyperpolarizing graded potential makes the membrane potential more negative (more polarized).
- A depolarizing graded potential makes the membrane potential less negative (less polarized).
- The amplitude of a graded potential varies, depending on the strength of the stimulus.
Action Potentials all-or-none principle
- if a stimulus is strong enough to generate an action potential, the impulse generated is of a constant size.
- A stronger stimulus does not generate a larger action potential.
- Instead, the greater the stimulus strength above threshold, the greater the frequency of the action potentials.
During an action potential, voltage-gated Na+ and K+ channels open and close in sequence.
This results first in depolarization, the reversal of membrane polarization (from −70 mV to +30 mV). Then repolarization, the recovery of the resting membrane potential (from +30 mV to −70 mV), occurs.
During the first part of the refractory period (RP), another action potential cannot be generated at all (absolute RP);
a little later, it can be triggered only by a larger-than-normal stimulus (relative RP).
an action potential travels from point to point along the membrane without getting smaller,
it is useful for long-distance communication
Nerve impulse propagation in which the impulse “leaps” from one myelin sheath gap to the next along a myelinated axon is saltatory conduction
. Saltatory conduction is faster than continuous conduction.