200's pharmo 2 Flashcards
Benzodiazapines
lorazepam (Ativan)
diazepam (Valium)
midazolam (Versed)
acts on GABA A receptors potentiating the effects of GABA
lorazepam dose 0.5-2mg SIVP
diazepam dose 5-10mg SIVP
midazolam dose 1-2.5mg SIVP
flumazenil (Anexate)
Benzo antagonist inhibiting actions of benzos on GABA
1st dose 0.2mg over 15 sec
2nd dose 0.3mg over 30 sec
3rd dose 0.5mg over 30 sec
phenobarbital (Luminal)
- anticonvulsant
- sedative
- Barbiturate
-increase the action of inhibitory neurotransmitters
100-250 mg SIVP
phenytoin (Dilantin)
- anticonvulsant
- sodium channel blocker
- promoting sodium efflux, stabilizing threshold
15-20mg/kg max 1000mg requires 5 things -blood work -inline filter -max 50mg/min -must be in NS (no D5)
haloperidol (Haldol)
- antipsychotic
- blocks dopamine receptors
2-5mg IM
dimenhydrinate (Gravol)
-antiemetic
- works on the inner ear
- 12.5-50mg
opioids morphine (Statex) 2-10mg SIVP fentanyl (Sublimaze) 0.5-1 mcg/kg SIVP meperidine (Demerol) 25-50mg SIVP nalbuphine (Nubain) 5mg SIVP redose 2mg SIVP
morpine and nalbuphine act on opiate receptors
fentanyl and mepridine act on Mu receptors
paralytics non-depolarizing -pancuronium (Pavulon) 0.04-0.1 mg/kg -rocuronium (Zemuron) 0.6-1.2 mg/kg -vecuronoim (Norcuron) 0.08-0.1 mg/kg
depolarizing
succinylcholine (Anectine) 1-1.5 mg/kg
non-depolarizing
-competes with ACH to bind to cholinergic receptors (prevents form ACH binding to cholinergic receptors)
depolarizing
combines with cholinergic receptors causing depolarization and delaying repolarization
neostigmine (Prostigmin)
-inhibits break down of ACH by acetylcholinesterase, ACH levels build up and allows for free transmission of nerve impulses
- 5-2 mg SIVP
- pretreat with atropine
ketamine (Ketalar) 0.5-1 mg/kg SIVP
dissociation of the limbic system and cortex
