20 clinical PK bioavailability

Question 1

What is bioavailability?

Answer 1

The proportion of the administered dose that reaches the systemic circulation

Question 2

What physicochemical factors affect bioavailability?

Answer 2

Solubility and dissolution

Question 3

What physiological and pathological factors influence bioavailability?

Answer 3

Metabolism and transporter activity in intestinal wall

Question 4

What is bioequivalence testing?

Answer 4

When new formulation is compared with the bran formulation

Question 5

What does bioequiavlence testing compare?

Answer 5

AUCs

Question 6

What is bioavailability?

Answer 6

The proportion of the administered dose that reaches the systemic circulation

Question 7

What physicochemical factors affect bioavailability?

Answer 7

Solubility and dissolution

Question 8

What physiological and pathological factors influence bioavailability?

Answer 8

Metabolism and transporter activity in intestinal wall

Question 9

What is bioequivalence testing?

Answer 9

When new formulation is compared with the bran formulation

Question 10

What does bioequiavlence testing compare?

Answer 10

AUCs