2- drug administration Flashcards
1
Q
Factors for orally administered drugs
A
Physiochemical interactions
Gi motility
Gi microflora
Mucosal dysfunction
2
Q
Best time to use oral drugs
A
Low molec weight
Lipid soluable
Acid resist
Liver metabolisim resist
3
Q
Advantages of oral meds
A
Easy to administer
Non invasive
May be reversible
4
Q
Characteristics of subcutaneous or su dermal injection
A
Good but slow absorption
Can be irritating
Inject over shoulders/neck
Solutions, suspensions, or solid formulations
5
Q
What physical-chemical properties enhance absorption
A
Small
Lipophilic
uncharged
6
Q
Advantages for transdermal
A
Constant rate of delivery
Simple
7
Q
Characteristics of IV
A
Preferred for large volumes
No absorption - 100% bioavailability
Allows precise control of plasma drug level
Particulate solutions only
