10 - Cholinergic Agents

Question 1

What stimulates cholinergic receptors

Answer 1

Ach

Question 2

2 receptor families

Answer 2

Muscarinic

Nicotinic

Question 3

Ach stimulates

Answer 3

Stimulates the poops
Treat GI disorders
Mucus from everywhere
-increased tear production

Question 4

Ach effect on respiration system

Answer 4

Increase mucus secretions

Use with a B2 agonist to treat asthma

Question 5

Ach effects on urinary system

Answer 5

Makes you pee

Question 6

Cholinergic agonist effect on eye

Answer 6

Constrict eye

Question 7

Parasympathetic stimulatory drug applications

Answer 7

Opthalmic exam
Glaucoma treatment
Tear production
Conjuctiva sicca treatment

Question 8

Parasympathetic effect on cardio

Answer 8

Reduction of heart rate

Part of baroreceptor reflex

Question 9

Parasympathetic effect on blood vessels

Answer 9

No direct effect

Mediated by NO

Question 10

Carbachol

Answer 10

Nicotenic and muscadine can agonist
-effective on GI and urinary tracts
potent drug
-toxic

Question 11

Bethanechol

Answer 11

Muscarinic 
Effective on GI and urinary tract
Promote contraction of urinary bladder
GI stimulant
No CNS action

Question 12

Pilocarpine

Answer 12

Alkaloid from Brazilian shrubs…because this is relevant and has a star next to it….

Question 13

Cholinergic agonists side effects

Answer 13

SLUD
-vomit, cramps, diarrhea
Respiratory distress
Bradycardia

Question 14

Atropine

Answer 14

MAch receptors

Cross b.b. Barrier

Question 15

BUSCOPAN

Answer 15

MAChR

Rectal exams

Question 16

Glycopyrrolate

Answer 16

mACh

Similar to atropine

Question 17

Use for anticholinergic agents

Answer 17

Reduce smooth muscle spasms
Anti secretory effects
Opthalmic exams
Prevent heart block
Antidote

Question 18

Side effect of cholinergic antagonists

Answer 18

Symptoms are an extension of the drugs
Dry mouth
Tachymydriasis
Colic
Ataxia