14: anti cancer Flashcards
1
Q
What is chemo best against
A
bone marrow
2
Q
What is chemo not so good against
A
sarcomas
3
Q
What does chemo target
A
rapidly dividing tissues
4
Q
Alkylating agents
A
non-specific
cross link DNA
different groups, same mechanism of action
class cross resistance
5
Q
cyclophosphamide class
A
cell cycle non specific
alkylating agent
6
Q
cyclophosphamide action
A
prodrug
crosslinks DNA
Inhibit protein synthesis
7
Q
cyclophosphamide use
A
lymphoma
hemangiosarcoma
soft tissue sarcoma
8
Q
cyclophosphamide side effects
A
Sterile hemorrhagic cystitis
transitional cell carcinoma
SIADHS
Hypoatremia
