11- Anticholenerestase Agents

Question 1

AChE actions

Answer 1

Break down ACh at the synapse

Question 2

Where are Ach actions mediated by musc. Receptors

Answer 2

CNS

Viseral organs

Question 3

BuChE examples

Answer 3

Aspirin
Cocaine
Heroine

Question 4

Function of BuChE

Answer 4

Break down ACh

Question 5

What are anti cholinesterase classifications based on

Answer 5

Duration of enzyme inhibition

Question 6

Effect of anti-cholinesterase

Answer 6

Inhibit AChE
Intensify ACh
Increased parasympathetic

Question 7

Therapeutic use of reversible anti-AChE receptors

Answer 7

Relief from glaucoma
GI stimulant
Diagnostic for myasthenia gravis
Anti parasitic

Question 8

Contraindications for anti AChE

Answer 8

Food animal
Severely sick animal
Respiratory issues
Pregnant

Question 9

Edrophonium

Answer 9

Short acting
Not hydrolyzed by AChE
Muscle relaxant

Question 10

Dose for Edrophonium

Answer 10

Dog:.1-.2 mg/kg
Cat: .5-1 mg/kg

Question 11

Neostigmine

Answer 11

Intermediate duration
Hydrolyzed by AChE
Does not cross bbb

Question 12

Actions of Neostigmine

Answer 12

Glaucoma
Treatment for m gravis
GI stimulant
Reversal for muscle relaxant

Question 13

Physostigmine

Answer 13

Greater CNS actions

Similar to Neostigmine

Question 14

Parathion main uses

Answer 14

Agricultural

• insecticide
• mosquitos control
• cattle dip

Question 15

Treatment of OP poisoning

Answer 15

Praladoxime

Question 16

OP poisoning

Answer 16

Inhaled: ocular, respiratory
Oral: GI, systemic
Cutaneous: sweating, muscle issues