18 - LARGE SCALE CHROMOSOMAL CHANGES AND THE DYNAMIC GENOME Flashcards
what are the effects of inversion on the frequency of recombinant progeny
you expect more recombinant progeny but the ones that had an inversion did not produce viable progeny
so they’re not counted and you get less recombinant progeny than expected
reminder of consequences of meiotic recombination in paracentric vs pericentric inversion heterozygote
what are chromosomal translocations
what is an example of a somatic consequence of a chromosomal translocation
what is a balanced translocation
When the break points do not impact a specific gene, and there is no gain or loss of chromosome material
how do balanced translocations segregate during meiosis
what is an acrocentric chromosome
a chromosome with a centromere near one end, resulting in one long arm and one short arm
what is a robertsonian translocation
a type of chromosomal abnormality where the long arms of two acrocentric chromosomes (chromosomes 13, 14, 15, 21, and 22) fuse together at the centromere, effectively creating one large chromosome
a type of balanced translocation
frequency: 1/1000
phenotype is usually normal
how does meiotic pairing occur when there is a robertsonian translocation
what are the 6 possible gametes that can arise from meiotic segregation of a robertsonian translocation carrier
what are the 6 possible outcomes in the zygote when the translocation carrier gametes fuse with normal gemetes
can result in trisomy or monosomy or normal
what is the pigment gene in maize and its alleles
the Coloured aleurone (C) gene is important for making purple pigment in maize
c is recessive: cannot make pigment, yellow corn
C1 is a dominance inhibitor allele that represses pigment production (yellow)
C is the dominant allele that gives the purple color
what is a way that chromosome 9 of maize is identifiable?
what happened when C1 (dominant negative) homozygous was crossed with C/C?
