17- IV Infusion Pharmacokinetics Flashcards
1
Q
What is the formula for after an IV infusion stops
A
s.IR
Ct = —– (1 – e-k.Tinf) e-k(t -Tinf)
Cl
2
Q
What is the formula for a continuous IV infusion
A
Citing = s.IR/Cl (1-e^-kTinf)
3
Q
What is the equation for an iv infusion at steady state
A
s.IR
Css = —–
Cl
4
Q
What does the steady state concentration of an IV depend on
A
Elimination half life
5
Q
What is the loading dose of N-acetylcysteine for paracetamol overdose
A
150mg/kg over 1hour
6
Q
What is the second infusion of N-acetylcysteine for paracetamol overdose
A
50mg/kg over 4hours
7
Q
What is the third infusion of N-acetylcysteine for paracetamol overdose?
A
100mg/kg over 16hours
