1.5d - Control of Programmed Cell Death (Apoptosis) Flashcards
Apoptosis is triggered by…
cell death signals that can be external or internal
Example of external death cell
the production of death signal molecules from lymphocytes
Example of internal death cell
DNA damage
External death signal molecules bind to a…
surface receptor protein and trigger a protein cascade within the cytoplasm
What causes the activation of the p53 tumour-suppressing protein?
an internal death signal resulting from DNA damage
Caspases are…
types of protease enzyme
Both types of death signal result in…
the activation of caspases that cause the destruction of the cell
Apoptosis is essential during…
the development of an organism to remove cells no longer required as development progresses of during metamorphosis
Cells may initiate the…
apoptosis in the absence of growth factors
