1.3a - Movement of Molecules Across Membranes Flashcards

1
Q

The fluid mosaic model envisions the membrane as a mosaic of…

A

protein molecules in a fluid bilayer of phospholipids, held by hydrophobic R groups forming hydrophobic interactions in the phospholipid bilayer

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2
Q

Hydrophobic interactions hold the bilayer together which…

A

repels any water instantly

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3
Q

Only non-polar molecules can…

A

diffuse across the bilayer

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4
Q

Regions of hydrophobic R groups allow…

A

strong hydrophobic interactions that hold integral membrane proteins within the phospholipid bilayer

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5
Q

Integral membrane proteins interact extensively with…

A

the hydrophobic region of membrane phospholipid

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6
Q

Some integral membranes are…

A

transmembrane proteins

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7
Q

Peripheral membrane proteins have hydrophilic R groups on their surface, bound to their surface by…

A

mainly ionic and hydrogen bond interactions

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8
Q

Many peripheral membrane proteins interact with…

A

the surfaces of integral protein membranes

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9
Q

The phospholipid bilayer is a…

A

barrier to ions and the most uncharged polar molecules

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10
Q

Small molecules eg oxygen and carbon dioxide, pass through the bilayer by…

A

simple diffusion

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11
Q

Facilitated diffusion is…

A

the passive transport of substances across the membrane through specific transmembrane proteins

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12
Q

To perform specialised functions…

A

different cell types have different channel and transporter proteins

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13
Q

Most channel proteins in animal and plant cells are…

A

highly selective

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14
Q

Channels are…

A

multi-subunit proteins with the subunits arranged to form water-filled pores that extend across the membrane

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15
Q

Some channel proteins are gated and…

A

change conformation to allow or prevent diffusion

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16
Q

Ligand-gated channels are controlled by…

A

the binding of signal molecules

17
Q

Voltage-gated channels are controlled by…

A

changes in ion concentration

18
Q

Transporter proteins bind to…

A

the specific substance to be transported

19
Q

Transporter proteins undergo…

A

a conformational change to transfer the solute across the membrane

20
Q

Transporters alternate between two conformations so that…

A

the binding site for a solute is sequentially exposed on one side of the bilayer, then the other

21
Q

Active transport uses pump proteins that transfer…

A

substances across the membrane against their concentration gradient

22
Q

Pumps that mediate active transport are…

A

transporter proteins coupled to an energy source

23
Q

What is required for active transport?

A

a source of metabolic energy

24
Q

Some active transport proteins hydrolyse ATP directly to…

A

provide energy for the conformational change required to move substances across the membrane

25
Q

What does ATPases do?

A

hydrolyse ATP

26
Q

The class of R-groups that predominate in the transmembrane
regions of proteins is…

A

non-polar