1.5b - The Cell Cycle Flashcards
The cell cycle consists of…
interphase and mitotic (M) phase
Interphase involves growth and DNA synthesis including…
G1, a growth phase; S phase, during which the DNA is replicated; and G2, a further growth phase
Mitotic phase involves…
mitosis and cytokinesis
Following mitosis is cytokinesis, in which…
the cytoplasm is separated into two daughter cells
Mitosis consists of…
prophase, metaphase, anaphase and telophase
Prophase
- DNA condenses into chromosomes each consisting of two sister chromatids
- Nuclear membrane breaks down; spindle microtubules extend from the MTOC by polymerisation and attach to chromosomes via their kinetochores in the centromere region
Metaphase
chromosomes are aligned at the metaphase plate (equator of the spindle)
Anaphase
as spindle microtubules shorten by depolymerisation, sister chromatids are separated, and the chromosomes are pulled to opposite poles
Telophase
the chromosomes decondense and nuclear membranes are formed around them