Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

AH Biology > 1.2ci - Protein Structure, Ligand Binding and Conformational Change > Flashcards

1.2ci - Protein Structure, Ligand Binding and Conformational Change Flashcards

1
Q

Proteins are polymers of…

A

amino acid monomers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Amino acids are linked by peptide bonds to form…

A

polypeptides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The chemical structure of a peptide bond involves…

A

two amino acids (OH and H) joining together to form water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Amino acids have the same basic structure, differing only in…

A

the R group present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The R groups of amino acids vary in…

A

size, shape, charge, hydrogen bonding capacity and chemical reactivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Amino acids are classified according to their R groups:

A

basic (positively charged), acidic (negatively charged), polar, hydrophobic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Basic amino acids have which R group?

A

NH2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Acidic amino acids have which R group?

A

COOH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Polar amino acids have which R group?

A

OH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hydrophilic amino acids have which R group?

A

Hydrocarbon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The wide variety of functions carried out by proteins results from…

A

the diversity of R grouups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The primary structure is…

A

the sequence in which amino acids are synthesised into the polypeptide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Hydrogen bonding along the backbone of the protein strand results in…

A

regions of secondary structure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Regions of secondary structure include…

A

alpha helices, parallel or anti-parallel beta-pleated sheets, or turns

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The polypeptide folds into…

A

a tertiary structure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The structure conformation is stabilised by…

A

interactions between R groups

17
Q

Regions of tertiary structure include…

A

hydrophobic interactions, ionic bonds, London dispersion forces, hydrogen bonds, disulphide bridges

18
Q

Disulphide bridges are…

A

covalent bonds between R groups containing sulphur

19
Q

Quaternary structure exists in…

A

proteins with 2 or more connected polypeptide subunits

20
Q

Quaternary structure describes…

A

the spatial arrangements of the subunits

21
Q

A prosthetic group is…

A

a non-protein unit tightly bound to a protein and necessary for its function

22
Q

The ability of haemoglobin to bind to oxygen is dependent upon the…

A

non-protein haem group

23
Q

Interactions of the R groups can be influenced by…

A

temperature and pH

24
Q

Increasing temperature disrupts the interactions that…

A

hold the protein in shape causing it to unfold and eventually become denatured

25
Q

The charges on acidic and basic R groups are affected by…

A

pH

26
Q

As pH increases or decreases from the optimum, the normal ionic interactions between charged groups are…

A

lost, which gradually changed the conformation of the protein until it is denatured

AH Biology (34 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions