15 Adrenal Cortex

Question 1

17-OHP values of classic and nonclassic CAH after ACTH stimulation

Answer 1

> 35 nmol/L or >1100 ng/dL

Question 2

17-OHP values of nonclassic CAH heterozygotes after ACTH stimulation

Answer 2

10-30 nmol/L or 330-1000 ng/dL

Question 3

Basal 17OHP in the follicular phase that effectively rules out 21-hydroxylase deficient nonclassic CAH

Answer 3

<5 nmol/L or <150 ng/dL

Question 4

Test used to confirm the clinical and biochemical diagnosis of 21-hydroxylase deficiency

Answer 4

CYP21A2 genotyping