14 Nontoxic Diffuse Goiter, Nodular Thyroid Disorders, Thyroid Malignancies Flashcards

1
Q

Identify the ATA risk:
Papillary thyroid cancer with no local or distant metastases

A

Low risk

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2
Q

Identify the ATA risk:
Papillary thyroid cancer with all macroscopic tumor resected

A

Low risk

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3
Q

Identify the ATA risk:
Papillary thyroid cancer with no tumor invasion of locoregional tissues or structures

A

Low risk

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4
Q

Identify the ATA risk:
Microscopic invasion of tumor into the perithyroidal soft tissues

A

Intermediate risk

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5
Q

Identify the ATA risk:
RAI-avid metastatic foci in the neck on the first posttreatment whole-body RAI scan

A

Intermediate risk

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6
Q

Identify the ATA risk:
Agressive histology (e.g., tall cell, hobnail variant, columnar fell carcinoma)

A

Intermediate risk

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7
Q

Enumerate three examples of aggressive histology that classifies a thyroid cancer under intermediate risk

A

Tall cell
Hobnail variant
Columnar cell

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8
Q

Identify the ATA risk:
Macroscopic invasion of the tumor into the perithyroidal soft tissues (gross extrathyroidal extension)

A

High risk

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9
Q

Identify the ATA risk:
Incomplete tumor resection

A

High risk

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10
Q

Identify the ATA risk:
Distant metastases

A

High risk

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11
Q

Identify ATA suspicion for malignancy:
Solid hypoechoic nodule with irregular margins

A

High suspicion

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12
Q

FNA size cutoff:
High suspicion sonographic pattern

A

≥1 cm

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13
Q

Estimated risk of malignancy:
Benign sonographic pattern

A

<1%

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14
Q

Estimated risk of malignancy:
Very low suspicion sonographic pattern

A

<3%

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15
Q

FNA size cutoff:
Intermediate suspicion sonographic pattern

A

≥1 cm

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16
Q

Estimated risk of malignancy:
Low suspicion sonographic pattern

A

5-10%

17
Q

Estimated risk of malignancy:
Intermediate suspicion sonographic pattern

A

10-20%

18
Q

FNA size cutoff:
Low suspicion sonographic pattern

A

≥1.5 cm

19
Q

Estimated risk of malignancy:
High suspicion sonographic pattern

A

> 70-90%

20
Q

Identify ATA suspicion for malignancy:
Purely cystic nodule

A

Benign

21
Q

FNA size cutoff:
Very low suspicion sonographic pattern (2)

A

> /=2 cm
Observation without FNA is also reasonable

22
Q

FNA size cutoff:
Benign sonographic pattern

A

No biopsy

23
Q

Identify ATA suspicion for malignancy:
Partially cystic nodule without eccentric sold areas

A

Very low suspicion

24
Q

Identify ATA suspicion for malignancy:
Spongiform nodule

A

Very low suspicion

25
Q

Identify ATA suspicion for malignancy:
Partially cystic nodule with eccentric sold areas

A

Low suspicion

26
Q

Identify ATA suspicion for malignancy:
Hyperechoic solid nodule

A

Low suspicion

27
Q

Identify ATA suspicion for malignancy:
Isoechoic solid nodule

A

Low suspicion

28
Q

Identify ATA suspicion for malignancy:
Solid hypoechoic nodule with smooth margins

A

Intermediate suspicion

29
Q

ATA US features that confer high suspicion of malignancy in solid hypoechoic nodule component (5)

A

Irregular margins (infiltrative, microlobulated)
Microcalcifications
Taller than wide shape
Rim calcifications with small extrusive soft tissue component
Extrathyroidal extension

30
Q

Positive predictive value of elastography in estimating malignancy risk

A

30-40%

31
Q

Physical half life of pertechnetate

A

6 hours

32
Q

Physical half life of iodine-131

A

8.1 days

33
Q

Physical half life of iodine-123

A

0.55 day