1.4di - Nerve Impulse Transmission Flashcards

1
Q

Resting membrane potential is…

A

a state where there is no net flow of ions across the membrane

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2
Q

The transmission of a nerve impulse requires…

A

changes in the membrane potential in the neuron’s plasma membrane

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3
Q

An action potential is…

A

a wave of electrical excitation along a neuron’s plasma membrane

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4
Q

Neurotransmitters initiate a response by…

A

binding to their receptors at synapse

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5
Q

Neurotransmitter receptors are…

A

ligand-gated channels

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6
Q

Entry of the positive ions causes…

A

the depolarisation of the plasma membrane

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7
Q

Depolarisation of the plasma membrane triggers…

A

the opening of voltage-gated sodium channels, and further depolarisation occurs

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8
Q

Depolarisation is…

A

a change in the membrane potential to a less negative value inside

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9
Q

What restores the resting membrane potential?

A

inactivation of the sodium channel and the opening of potassium channels

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10
Q

Binding of a neurotransmitter triggers…

A

the opening of ligand-gated ion channels at a synapse

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11
Q

Ion movement occurs and…

A

there is depolarisation of the plasma membrane

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12
Q

What triggers the opening of voltage-gated sodium channels?

A

if sufficient ion movement occurs, and the membrane is depolarised beyond a threshold value

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13
Q

The opening of voltage-gated sodium channels causes…

A

sodium ions to enter the cell down their electrochemical gradient, leading to a large and rapid change in the membrane potential

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14
Q

A short time after opening, the sodium channels…

A

become inactivated

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15
Q

After the sodium channel are deactivated…

A

voltage-gated potassium channels open to allow potassium ions to move out of the cell to restore the resting membrane potential

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16
Q

Depolarisation of a patch of membrane causes…

A

neighbouring regions of membrane to depolarise and go through the same cycle, as adjacent voltage-gated sodium channels are opened

17
Q

When the action potential reaches the end of the neuron it causes…

A

vesicles containing neurotransmitters to fuse with the membrane, which releases a neurotransmitter, stimulating a response in a connecting cell

18
Q

Restoration of the resting membrane potential allows…

A

the inactive voltage-gated sodium channels to return to a conformation that allows them to open again in response to depolarisation of the membrane

19
Q

Ion concentration gradients are re-established by…

A

the sodium-potassium pump, which actively transports excess ions in and out of the cell

20
Q

Following repolarisation…

A

the sodium and potassium ion concentration gradients are reduced

21
Q

The sodium-potassium pump restores…

A

the sodium and potassium ions back to resting potential levels