13: Peds Flashcards

1
Q

What are the two most common types of Pediatric cancer?

A

Brain/CNS
Leukemia

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2
Q

What are nutrition concerns for Acute Lymphoblastic Leukemia (ALL) in Peds?

A

Malnutrition during therapy can affect disease response, infection risk, toxicities and treatment delays

ALL pts are at risk for obesity during maintenance and continuation phases of treatment but its preventable. They are also at risk for bone mineral density issues from the treatment

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3
Q

What are nutrition concerns for Acute Myeloid Leukemia (AML) in Peds?

A

Nutritional status at diagnosis can effect outcomes, particularly if unhealthy weight (below 5th% or above 85%)

Prone to anorexia, wt loss, nausea/vomiting, mucositis and malnutrition due to the chemo.

Cardiomyopathy is a common late effect of treatment

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4
Q

What are nutrition concerns for CNS Tumors (Brain) in Peds?

A

Dysphagia for patients with posterior fossa brain tumors and for those with progressive disease that affects the cerebellum/brainstem areas.

Long term complications are cognitive and motor skill deficits, wt gain, central adiposity, and feeding difficulties. Radiotherapy may adjust ghrelin and leptin cues, causing excessive intake

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5
Q

What are nutrition concerns for Hodgkin Lymphoma in Peds?

A

3rd most common

significant wt loss may be presenting symptom of HL (and non-HL) however steroids can also cause wt gain

Mediastinal radiation can cause abnormal thyroid, heart, and lung function. Anthracyclines further increase cardiovascular risk.

Survivors are at increased risk for breast, thyroid, and skin cancers

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6
Q

What are nutrition concerns for Non-Hodgkin Lymphoma (NHL) in Peds?

A

N/V, anorexia, and constipation. Fluid retention and hyperglycemia from steroids.

Survivors are at risk for cardiomyopathy and other cancers. As well as obesity, HTN, impaired mobility and reduced strength.

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7
Q

What are nutrition concerns for Neuroblastoma in Peds?

A

most common solid tumor–often diagnosed after 1st year of life

Malnutrition appears in 20-50% of cases.

Late effects include underweight, diseased growth and development (after HCT), musculoskeletal complications, neurological complications and endocrine complications

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8
Q

What are nutrition concerns for Rhabdomyosarcoma in Peds?

A

short-term treatments may cause anorexia, constipation and jaw pain.

Late effects may include SBO, esophageal strictures, renal tubular dysfunction and secondary malignancies. Radiotherapy to Head/neck area may cause dental problems and growth hormone deficiency

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9
Q

What are nutrition concerns for Wilms Tumor in Peds?

A

Most common kidney cancer in kids

malnutrition at diagnosis may cause anorexia and early satiety from the growing tumor.

whole abd or flank radiation may increase risk for radiation enteritis.

Late effects may include cardiotoxicity and 2nd malignancies. ESRD occurs occasionally in patients with bilateral disease

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10
Q

What are nutrition concerns for Osteosarcoma in Peds?

A

most common bone tumor, typically occurs in extremities during periods or rapid growth with pain being the most common presenting symptom.

Surgery may involve amputation or limb-salvage surgery.

Malnutrition is exacerbated by treatment with the incidence of underweight status increasing from 7.8% at diagnosis to 36% a year later

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11
Q

What are nutrition concerns for Ewing Sarcoma in Peds?

A

2nd most common bone

abnormal BMI at diagnosis is associated with poorer response at time of surgical resection.

surgery and radiation may significantly affect functional status, mobility, and growth

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12
Q

What is a long term effect from childhood cancer that could have lasting health concerns?

A

change in body composition — increased fat mass and decreased lean mass

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13
Q

To review a single point of data to indicate malnutrition, what are the ranges for mild/moderate/severe malnutrition?

A

-1 to -1.9 for mild — for Wt-for-Ht z score, BMI-for-age z score, mid-upper arm circumference z score

-2 to -2.9 for moderate — for Wt-for-Ht z score, BMI-for-age z score, mid-upper arm circumference z score

-3 or less for severe — for Wt-for-Ht z score, BMI-for-age z score, mid-upper arm circumference z score PLUS length/Ht-for-age z score

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14
Q

To review a 2 or more points of data to indicate malnutrition, what are the ranges for mild/moderate/severe malnutrition?

A

Wt gain (if under 2)— <75% of expected wt gain for age is mild, <50% is moderate, <25% is severe

Weight loss (2-20 yrs) — 5% of usual weight is mild, 7.5% is moderate, 10% is severe

Deceleration of wt-for-length or BMI z scores —- decline of 1 z score is mild, 2 is moderate, 3 is severe

inadequate intake — 51-75% of estimated needs is mild, 26-50% is moderate, <25% is severe

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15
Q

What is the nutrition tool for Peds?

A

Nutrition Screening Tool for Childhood Cancer (SCAN)

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16
Q

What could be the true cause of an elevated Ferritin Level?

A

Inflammation - often falsely elevated

17
Q

What is a nutritional concern for Vitamin D levels? What is an appropriate minimum level for patients/survivors?

A

Often deficient in patients, supplement likely needed — important for bone health and immune health

30 mg/mL for 25-hydroxyvitamin D

18
Q

Why should Lipase be monitored in peds patients?

A

patients can develop pancreatitis from chemo, including steroids or asparaginase

19
Q

What unique pediatric population is at higher risk for leukemia?

A

individuals with Down Syndrome — consider baseline feeding practices and likelihood or maintaining these practices throughout treatment when assessing nutrition risk

20
Q

What macronutrient might need to be greatly increased? Will it alone address wasting?

A

Protein — sometimes 150-200% of the RDA to attempt to avoid/limit wasting

No, still need to make sure calories overall are adequate too