13. Alteraciones de la pigmentación Flashcards

1
Q

causa de discromia con hipopigmentacion

A

disminucion o la ausencia total de la melanina o de melanocitos en la epidermis

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2
Q

enfermedad clasica de discromia con hipopigmentacion

A

vitiligo

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3
Q

que es vitiligo

A

maculas acromicas por destruccion de melanocitos

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4
Q

epidemiologia de vitiligo

A

1% de la poblacion
incia en infancia y juventud
caracter familiar
herencia multifacterial

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5
Q

etiopatogenia autoinmune de vitiligo

A

se asocia con otras enfemedades autoinmunes

se pueden detectar Ac antimelanocito

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6
Q

enfermedades autoinmunes asociadas a vitiligo

A

anemia perniciosa
enfermedad de graves
enfermedad de addison

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7
Q

etiopatogenia autocitotoxica en vitiligo

A

autodestruccion de melanocitos por exceso de funcion y formacion de radicales libres

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8
Q

etiopatogenia neural en vitiligo

A

basada en evidencia de vitiligos segmentarios presencia de vitiligo en areas denervadas y en modelos animales

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9
Q

cliica de vitiligo generalizado

A

el mas habitual

placas simetricas en superficies extensoras de cuello, extremidades, axiales y cara

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10
Q

clinica de vitiligo focal

A

placas unicas sin distribucion en dermatomas

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11
Q

clinica de vitiligo segmentario

A

afecta a un dermatoma de forma asimetrica

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12
Q

cliica de vitiligo universal

A

perdida completa de pigmento

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13
Q

tratamiento de vitiligo localizado

A

corticoides topicos

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14
Q

tratamiento de vitiligo extensores o generalizadas

A

UVB o PUVA

khellin con fototerapia

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