12.7 Preventing & Treating Disease Flashcards
What are the different types of immunity?
natural/artificial
active/passive
What is natural active immunity?
immunity arising from
body’s response to a PATHOGEN INVASION
What is natural passive immunity?
immunity
given to INFANT mammal by mother
through PLACENTA + COLOSTRUM
What is artificial active immunity?
immunity arising from
the ADMINISTRATION of ANTIBODIES from another animal
What is artificial passive immunity?
immunity arising from
the EXPOSURE to a SAFE FORM of a PATHOGEN
What occurs during a PATHOGEN INVASION to build NATURAL ACTIVE immunity?
• pathogen is detected for first time - triggers PRIMARY response
◦ immune system activated, produces ANTIBODIES
◦ antibodies BIND to complementary antigen
◦ pathogen ENGULFED by PHAGOCYTE
• Immune system produces T + B MEMORY cells - SECONDARY response
◦ if pathogen met again, antigens recognised
◦ produces complementary antibodies @ FASTER RATE + HIGHER CONCENTRATION than primary response
How is the secondary immune response different from the primary?
secondary produces antibodies at:
- Faster rate
- Higher concentration
How does natural passive immunity arise?
• ANTIBODIES CROSS PLACENTA from mother ⟶ fetus while in uterus
◦ Infant has some immunity at birth
• COLOSTRUM is high in ANTIBODIES
◦ Infant gut cannot digest antibodies, so pass into bloodstream
◦ Results in baby having same level of immunity as mother
- antibodies received are relevant to environment, since acquired by mother
How does artificial active immunity arise?
Antibodies are produced by individual
in response to dead/inactive pathogen in vaccine
How does artificial active immunity arise?
- Small amounts of VACCINE injected into bloodstream
- (contains different substances depending on method used to make pathogen safe) - Triggers primary immune RESPONSE»_space; produces ANTIBODIES + MEMORY cells specific to pathogen
- SECONDARY immune response destroys pathogens BEFORE SYMPTOMS
- T + B memory cells RECOGNISE antigen + produce antibodies faster