1.2 Principles of Physiology Flashcards

1
Q

What questions does physiology as an integrating science seek to answer about a system?

A

how a system evolved and what survival advantages this feature provided.

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2
Q

__ reflects evolution, showing how developmental processes mirror evolutionary history.

In the context of physiology, the organs and systems that develop in an organism follow patterns that have been shaped by millions of years of evolution. The way these structures develop in an embryo can give clues to their evolutionary origins, showing how current physiological traits have been adapted and refined over time.

A
  • Ontogeny
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3
Q

It means that physiology brings together everything known about an animal’s function to create a comprehensive picture of how the animal operates in its environment.

A

physiology as an integrative science

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4
Q

study the structure and function of various parts of animals and plants, and how these parts work together to allow organisms to perform normal behaviors and respond to their environment.

A

Physiologist

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5
Q

learn about the control and regulation of processes within groups of cells and how the combined activities of these cell groups affect the function of the animal.

A

design experiments

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6
Q

How do physiologists contribute to understanding an organism’s function?

A

By studying how different parts work together and designing experiments, physiologists gain insights into how organisms perform their normal behaviors and respond to their environment.

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7
Q

a hallmark of physiology because meeting the demands of survival has led to numerous evolutionary variations on the basic theme of life.

A

Diversity

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8
Q

What do physiological processes obey? (2)

A

physical and chemical laws.

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9
Q

How are physiological processes regulated? (2)

A
  • maintain internal conditions
  • to trigger an appropriate response.
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10
Q

The physiological state of an animal is part of its __, which arises from the interaction between its genetic make-up (__) and the environment.

A
  • phenotype
  • genotype
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11
Q

What are the subdisciplines of physiology (5)?

A
  • Comparative Physiology
  • Environmental Physiology
  • Evolutionary Physiology
  • Developmental Physiology
  • Cell Physiology
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12
Q

A subdiscipline of physiology that explores how physiological processes unfold during the development of an organism from embryo through larva or fetus to adulthood.

A

Developmental Physiology

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13
Q

A subdiscipline of physiology that compares species to discern physiological and environmental patterns.

A

Comparative Physiology

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14
Q

A subdiscipline of physiology that examines organisms in the context of the environments they inhabit, focusing on evolutionary adaptations.

A

Environmental Physiology

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15
Q

A subdiscipline of physiology that uses techniques of evolutionary biology and systematics to understand the evolution of organisms from a physiological viewpoint, focusing on physiological markers rather than anatomical markers.

A

Evolutionary Physiology

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16
Q

A subdiscipline of physiology that provides vital information on the physiology of cells themselves, which can be used to understand the physiological responses of tissues, organs, and organ systems.

A

Cell Physiology

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17
Q

What are the 3 central themes in Physiology?

A
  1. Structure/Function Relationships
  2. Adaptation, Acclimatization, and Acclimation
  3. Homeostasis
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18
Q
  • Knowledge of a __ provides insight into what it does and how it works.
  • Knowing the function of a __ provides insight into its __.
A
  • structure
  • structure; construction
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19
Q

Give an example of how the structure-function relationship is evident in bird wings.

A

The aerodynamic efficiency of a bird’s wings; a honeycombed internal structure produces light but strong bones, flight muscles are controlled by neurons, and ample mitochondria provide the energy for flight.

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20
Q

Give an example of the structure-function relationship are evident in carnivores and ruminant herbivores.

A

the anatomical features of these animals are directly related to their dietary needs and feeding behaviors.
- ruminant herbivores’ complex stomach and digestive processes reflect their need to efficiently break down and absorb nutrients from plant material.
- carnivorous animals’ streamlined digestive system and specialized teeth reflect their need to process meat quickly and effectively.

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21
Q

Evolution through natural selection leading to an organism whose physiology, anatomy, and behavior are suited to its environment. It is generally irreversible.

A

Adaptation

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22
Q

if it is present at high frequency in the population because it results in a higher probability of survival and reproduction than alternative processes.

A

adaptive

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23
Q

How are physiological and anatomical adaptations passed on?

A

They are genetically based, passed on from generation to generation (DNA), and shaped and maintained by natural selection.

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24
Q

A physiological, biochemical, or anatomical change within an individual that results from chronic exposure to new, naturally occurring environmental conditions in its native habitat.

A

Acclimatization

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25
Q

Refers to the same physiological changes as acclimatization but induced experimentally in a laboratory or by an investigator, such as placing an animal in a hypobaric chamber.

A

Acclimation

26
Q

both acclimatization and acclimation are

A

Reversible

27
Q

What is the concept of “milieu intérieur” introduced by Claude Bernard?

A

refers to the internal environment of an organism, emphasizing that its constancy is crucial for free life.

28
Q

What did Claude Bernard mean by “Constancy of the internal environment is the condition of free life”?

A

ability of animals to survive in stressful and varying environments depends on their ability to maintain a stable internal environment.

29
Q

What did Walter B. Cannon extend the notion of internal consistency to?

A

organization and function of cells, tissues, and organs.

30
Q

When did Walter B. Cannon introduce the concept of homeostasis, and what recognition did he receive for it?

A

in 1929 and was awarded the Nobel Prize for it.

31
Q

Insulin and glucagon are __ hormones that help maintain glucose homeostasis.

A

antagonistic

32
Q

Insulin and glucagon are produced by clusters of endocrine cells called __, with alpha cells producing glucagon and beta cells producing insulin.

A

islets of Langerhans

33
Q

A condition associated with diabetes mellitus, characterized by insufficient insulin production or function.

A

Hypoinsulinism

34
Q

Symptoms include excessive urination and excessive thirst. Complications include high blood sugar levels, sugar excreted in the urine, and if severe, the substitution of fat for glucose as a major fuel source, leading to life-threatening acidic metabolites and a dangerous lowering of blood pH.

A

Hypoinsulinism: diabetes mellitus

35
Q

What are some symptoms and complications of diabetes mellitus? when will it become life-threatening?

A

symptopms: excessive urination and excessive thirst.
complications: high blood sugar levels, sugar excreted in the urine, and if severe, the substitution of fat for glucose as a major fuel source, leading to life-threatening acidic metabolites and a dangerous lowering of blood pH.

36
Q

is an autoimmune disorder that usually appears in childhood and is treated with insulin injections.

A

Type I diabetes mellitus (insulin-dependent diabetes mellitus)

37
Q

usually occurring after age 40 and increasing with age, is due to target cells having decreased responsiveness to insulin and accounts for over 90% of diabetes cases.

A

Type II diabetes mellitus (insulin-independent diabetes mellitus)

38
Q

a condition caused by the overproduction of growth hormone (GH), usually due to a benign pituitary tumor, leading to abnormal growth in bones and tissues.

A

Acromegaly

39
Q

GH secretion is regulated by a __ feedback mechanism involving the __ and __. High GH levels cause the __ to reduce growth hormone-releasing hormone (GHRH) and increase somatostatin, lowering GH production.

A
  • negative
  • hypothalamus
  • pituitary gland
  • hypothalamus
40
Q

In acromegaly, the feedback loop is disrupted because the pituitary tumor continuously produces __, overriding the body’s normal regulatory mechanisms.

A

growth hormone (GH)

41
Q

animals that can survive large fluctuations in external osmolarity, allowing them to live in environments with varying salinity levels.

A

Euryhaline animals

42
Q

An adaptation that allows some aquatic invertebrates to survive in temporary waters. Allows to lose almost all their body water and survive in a dormant state.

A

Anhydrobiosis

43
Q

What is an example of an organism that uses anhydrobiosis?

A

tardigrade

44
Q

In which type of environment are animals that undergo anhydrobiosis typically found?

A

temporary waters

45
Q

essential for maintaining homeostasis in cells and multicellular organisms by regulating controlled variables through the return of information to a controller.

A

Feedback mechanisms

46
Q

a controller that regulates a controlled variable within the system.

A

control system

47
Q

(pH regulation in duodenum) What triggers the feedback loop that regulates pH in the duodenum?

A

The arrival of acidic chyme from the stomach into the duodenum, which lowers the pH, triggers the feedback loop.

48
Q

(pH regulation in duodenum) Which specialized cells detect the low pH in the duodenum?

A

S cells in the lining of the duodenum

49
Q

(pH regulation in duodenum) What hormone is released by S cells in response to low pH in the duodenum?

A

secretin

50
Q

(pH regulation in duodenum) What is the response of the pancreas when secretin binds to its receptors?

A

releases bicarbonate ions (HCO3-) into the duodenum.

51
Q

(pH regulation in duodenum) What is the role of bicarbonate ions in the feedback loop?

A

neutralizes the acidic chyme, raising the pH in the duodenum.

52
Q

Childbirth feedback mechanisms: How does the positive feedback loop continue during labor?

A

As contractions occur, the baby’s head pushes more against the cervix, causing further stretching. This increased stretching leads to more oxytocin release, intensifying contractions. This cycle of contraction, cervical stretching, and oxytocin release continues until childbirth is complete.

53
Q

Breastfeeding feedback mechanisms: How does the release of oxytocin facilitate milk ejection during breastfeeding? What role does the positive feedback loop play in milk ejection?

A

During breastfeeding, the baby’s sucking stimulates sensory receptors in the nipple, sending signals to the hypothalamus. The hypothalamus then signals the posterior pituitary gland to release oxytocin, which causes the milk ducts to contract and eject milk for the baby to drink.

The baby’s continued sucking stimulates more oxytocin release, leading to further milk ejection. This positive feedback loop ensures that as the baby suckles more, more oxytocin is released, enhancing the milk ejection process.

54
Q

Experience internal body changes that directly parallel external conditions, meaning they cannot maintain homeostasis and their internal environment changes with external conditions.

A

Conformers

55
Q

Give examples of conformers (2 types)

A
  • osmoconformers like sharks and starfish
  • oxyconformers like annelid worms.
56
Q

use biochemical, physiological, and behavioral mechanisms to maintain homeostasis and regulate their internal environment over a broad range of external changes.

A

Regulators

57
Q

maintain ion concentrations in their body fluids above or below environmental levels, depending on the external conditions. For example, they regulate their internal ion concentrations when placed in dilute water or in more concentrated environments to ensure stable internal conditions.

A

Osmoregulators

58
Q

Freshwater fish conformers actively __ salts and __ excess water to handle low salinity.

Marine fish conformers __ seawater and __ excess salts to manage high salinity, allowing their internal conditions to match external conditions.

A
  • absorb
  • excrete
  • drink
  • excrete
59
Q

Freshwater fish regulators __ excessive water gain and __ salt levels to adapt to low salinity.

Marine fish regulators __ salt and water balance to cope with the high salinity of their environment, maintaining internal stability despite external changes.

A
  • prevent
  • maintain
  • manage
60
Q

based on the controlled movement of solutes between internal fluids and the external environment. This regulation ensures the balance of solute concentrations and water content within the organism, maintaining homeostasis.

A

Osmoregulation

61
Q

Seagulls consume seawater and use specialized __ near their eyes to excrete excess salt from their __, which is expelled through their __ as a concentrated solution. They also produce concentrated urine to __ water, allowing them to maintain internal water and salt balance in high salinity environments.

A
  • salt glands
  • bloodstream
  • nostrils
  • conserve